点击显示 收起
May 15, 2007 – Why do certain diets work for some people and not for others? Blame biology, a new study suggests.
The study shows that obese people using a weight loss strategy called the low-glycemic-load diet lost nearly 13 pounds over a year and a half -- but only if their bodies secreted high amounts of insulin in response to sugars.
Obese high-insulin secretors who tried a low-fat diet lost only 2.5 pounds. On the other hand, people who were low-insulin secretors lost the same amount of weight -- a little more than 4 pounds after a year and a half -- on low-glycemic-load and low-fat diets.
"The low-glycemic-load diet was effective for a lot of the individuals who were high-insulin secretors and who previously had challenges losing weight and keeping it off," study researcher Cara B. Ebbeling, PhD, co-director of obesity research at Children's Hospital Boston, tells WebMD.
Ebbeling, David S. Ludwig, MD, PhD, and colleagues report the findings in the May 16 issue of the Journal of the American Medical Association.