100 Worst Spring Allergy Cities

April 24, 2008 -- Lexington, Ky., tops the Asthma and Allergy Foundation of America's 2008 list of "spring allergy capitals."

Greensboro, N.C., takes second place, followed by Johnson City, Tenn., Augusta, Ga., and Jackson, Miss. in fifth place.

The annual list is based on four factors: allergy prevalence, seasonal pollen, allergy medication use per patient, and the number of board-certified allergy specialists per patient. Rankings can change quite a bit from year to year. For instance, Lexington leads this year's rankings but was in the No. 52 spot on the 2007 list.

Here is the complete list of 2008 spring allergy capitals:

1. Lexington, Ky.
2. Greensboro, N.C.
3. Johnson City, Tenn.
4. Augusta, Ga.
5. Jackson, Miss.
6. Knoxville, Tenn.
7. Birmingham, Ala.
8. New Orleans
9. Little Rock, Ark.
10. San Diego
11. Oklahoma City
12. Mobile, Ala.
13. South Bend, Ind.
14. Omaha, Neb.
15. Stockton, Calif.
16. McAllen, Texas
17. Greenville, S.C.
18. Nashville, Tenn.
19. Tulsa, Okla.
20. Harrisburg, Pa.
21. Louisville, Ky.
22. Dallas-Fort Worth
23. Charlotte, N.C.
24. Tampa, Fla.
25. Philadelphia
26. St. Louis
27. Scranton, Pa.
28. Lansing, Mich.
29. Madison, Wis.
30. Rochester, N.Y.
31. Daytona Beach, Fla.
32. Memphis
33. Milwaukee, Wis.
34. Norfolk, Va.
35. Pensacola, Fla.
36. Charleston, S.C.
37. Cleveland, Ohio
38. Indianapolis
39. Houston
40. Lakeland, Fla.
41. Baltimore
42. Sacramento, Calif.
43. Columbia, S.C.
44. Kansas City, Mo.
45. New York
46. San Antonio
47. Allentown, Pa.
48. Wichita, Kan.
49. Albuquerque, N.M.
50. Baton Rouge, La.
51. Washington, D.C.
52. Providence, R.I.
53. Fort Wayne, Ind.
54. Austin, Texas
55. Canton, Ohio
56. Atlanta
57. Kalamazoo, Mich.
58. Chattanooga, Tenn.
59. Boston
60. Detroit
61. Grand Rapids, Mich.
62. Hartford, Conn.
63. Denver
64. Dayton, Ohio
65. Tucson, Ariz.
66. Buffalo, N.Y.
67. Des Moines, Iowa
68. Syracuse, N.Y.
69. Salt Lake City
70. Minneapolis-St. Paul
71. Cincinnati
72. Columbus, Ohio
73. Chicago
74. Boise City, Idaho
75. Albany, N.Y.
76. El Paso, Texas
77. Richmond, Va.
78. Raleigh-Durham-Chapel Hill, N.C.
79. Las Vegas
80. Jacksonville, Fla.
81. Melbourne, Fla.
82. Pittsburgh
83. Miami
84. Toledo, Ohio
85. Modesto, Calif.
86. Los Angeles
87. Springfield, Mass.
88. Youngstown, Ohio
89. Colorado Springs, Colo.
90. Seattle
91. Phoenix-Mesa, Ariz.
92. Fresno, Calif.
93. Portland, Ore.
94. Fort Myers, Fla.
95. Orlando, Fla.
96. Lancaster, Pa.
97. Sarasota, Fla.
98. Bakersfield, Calif.
99. San Francisco
100. Spokane, Wash.