Literature
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PRISM-PLUS: Demographics of Patients With Diabetes
 Patients Without Patients With
 Diabetes Diabetes
 (n=1208) (n=362)
Mean age (y)  62   66
Prior MI  40%   47%
Heart failure  7%   16%
PTCA  31%   28%
CABG  23%   24%
PRISM-PLUS: MI/Death Outcomes in Patients With Diabetes
% Patients
9.3%
1.2%
P=0.004
15.5%
4.7%
P=0.002
19.2%
11.2%
P=0.044
Day 7
Day 30
Day 180
PRISM-PLUS: MI in Patients With Diabetes
% Patients
7.8%
0%
P<0.001
11.4%
1.8%
P=0.002
13.5%
4.7%
P=0.008
Day 7
Day 30
Day 180
PRISM-PLUS: Results in Patients With Diabetes
Conclusion
Tirofiban + heparin therapy resulted in a marked sustained reduction in major cardiac outcomes, particularly recurrent MI, in patients with diabetes presenting with UAP/NQWMI.
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