Literature
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In-stent Restenosis
SIRIUS: 8 Month Angiographic Follow-up Restenosis Rates
In-segment Restenosis
Sirolimus
Stent
Bare
Stent
91% reduction
p<0.001
Sirolimus
Stent
Bare
Stent
75% reduction
p<0.001
Late Lumen Loss (mm)
Sirolimus
Stent
Proximal Margin
p<0.001
SIRIUS: 8 Month Angiographic Follow-up Late Lumen Loss
Bare
Stent
In-stent
p<0.001
Distal Margin
p<0.001
Sirolimus
Stent
Bare
Stent
Sirolimus
Stent
Bare
Stent
Number of In-segment Restenosis Events Prevented per 100 Patients
All patients
SIRIUS: Restenosis Events Prevented
Diabetes
LAD
Small
Vessels
Long
Lesions
MACE
SIRIUS: Clinical Events Through 9 Months
Target Vessel Failure*
Sirolimus
Stent
Bare
Stent
Sirolimus
Stent
Bare
Stent
*Primary clinical endpoint; defined as
cardiac death, MI, TVR
p<0.001
p<0.001
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