Literature
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1224 STEMI pts, no reperfusion, < 24 hours from onset
4 treatment groups
Enox 30 mg iv plus 1 mg/Kg sc bd alone
Enox 30 mg iv plus 1 mg/Kg sc bd with Aggrastat 100 ug/Kg IV
UFH 70 U/Kg plus 15 U/Kg per hour infusion
UFH 70 U/Kg plus 15 U/Kg inf. with Aggrastat 100 ug/Kg IV
Subgroup analysis showed protective Tirofiban trend in:
Pts treated within 12 hours
LV dysfunction
Study underpowerd for mortality
Treatment with Enoxaparin and Tirofiban in acute MI (TETAMI) M.Cohen et al, Beth Israel Hospital, NJ
Outcomes in TETAMI
Cohen M. American Heart Association Scientific Sessions 2002.
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