摘要：Here, a loss-of-function mutation (G304E) in the c-Cbl TKB domain, first identified in Caenorhabditis elegans, was introduced into a mouse and its effects in thymocytes and T cells were studied。 I...

摘要：, which exert similar activities through the IL-1R type 1 (IL-1R1。 Adoptive Transfer of In Vitro–restimulated CD4+ T Cells and DC Treatment Protocol。 Myocarditis Prevalence and Severity in IL-1R...

摘要：Accessibility of regions of the GM-CSF gene to MNase digestion。 Primer Sequences for SYBR Green Real-Time PCR Analysis Chromatin Accessibility by Real-Time PCR。Accessibility of DNA to digestion w...

摘要：Dynamics and requirements of T cell clonal expansion in vivo at the single cell level: effector function is linked to proliferative capacity。 Dynamic imaging of T cell-dendritic cell interactions ...

摘要：1 Unité de Biologie Moléculaire du Gène, INSERM U277 and Institut Pasteur, 75724 Paris Cedex 15, France2 Laboratory of Molecular Immunology, Howard Hughes Medical Institute, The Rockefeller Univ...

摘要：D‘Annunzio, 66100 Chieti, Italy2 Laboratory of Clinical Biochemistry, Istituto Superiore di Sanità, 00161 Rome, Italy3 Laboratory of Cell Biology, Istituto Superiore di Sanità, 00161 Rome, Italy...

摘要：We demonstrate that human neutrophils, after incubation with G-CSF or, less efficiently, IFN, express high levels of BLyS mRNA and release elevated amounts of biologically active BLyS。 Worthy of n...

摘要：Here we demonstrate that CD4+ T cells that recognize a secreted tumor-specific antigen and exhibit a cytokine secretion profile characteristic of Th2 cells, are capable of clearing established lung...

摘要：Cytokine receptors are potential candidates for transducing signals that maintain thymocyte differentiation after TCR signaling has ceased (9–11), although most of what is known about cytokine rec...

摘要：1 make essential and mostly overlapping contributions necessary for B cell migration into white pulp cords。1 function together to promote lymphocyte transit from the marginal zone into white pulp ...

摘要：Serum Transfer and Arthritis Scoring。 ResultsTopAbstractIntroductionMaterials and MethodsResultsDiscussionReferencesIL-1 Signaling Is Critical to Development of Serum Transferred Arthritis。

摘要：(c) Penetrance of case-definition infectious diseases in the 12 IL-12Rß。 Clinical Penetrance and Impact of BCG on Clinical Phenotype。

摘要：Induction, Assessment of Arthritis and Histological Examination。 ResultsTopAbstractIntroductionMaterials and MethodsResultsDiscussionReferencesAdoptive Transfer of Anti-CD40–treated Splenocytes ...

摘要：Instituto Gulbenkian de Ciência, 2781-901 Oeiras, Portugal AbstractTopAbstractIntroductionMaterials and MethodsResultsDiscussionReferencesRegulatory CD4 T cells (Treg) control inflammatory reacti...

摘要：1 Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 208922 Experimental Immunology Branch, Center for Cancer Rese...

摘要：Division of Immunology, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720 AbstractTopAbstractIntroductionMaterials and MethodsResults and DiscussionReferencesC...

摘要：1 Departments of Medicine/Rheumatology and Immunology, Mayo Clinic, Rochester, MN 559052 Centre d‘Immunologie de Marseille-Luminy, CNRS-INSERM-Université de la Méditerranée, Campus de Luminy, C...

摘要：Sustained adhesion of progenitor B cells is associated with prolonged FAK activation, whereas transient adhesion in circulating B cells is associated with short-lived FAK activation。 Cell Culture ...

摘要：CD4 T cells IntroductionTopAbstractIntroductionMaterials and MethodsResultsDiscussionReferencesRegulation or control of responsiveness is an intrinsic property of the immune system。 Cells that ar...

摘要：Mary‘s Campus, London W2 1PG, United Kingdom AbstractTopAbstractIntroductionMaterials and MethodsResultsDiscussionReferencesToll-like receptors (TLRs) are crucial in the innate immune response t...

摘要：1 Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada2 Centre for Molecular Medicine, Ottawa Hospital Research Institute, Ottawa, Ontario ...