摘要:Vascular endothelial growth factor (VEGF), a well-established angiogenesis factor has been recently found to have potent pro-inflammatory properties in the early period after transplant。 J Biol Ch...
08-05-29摘要:【摘要】 The transcription factor Pax2 is known to play a key role during renal development and to act as an oncogene favoring renal tumor growth。 In the present study we found that renal tum...
08-05-29摘要:Elastase and Collagenase AssayProtease assays were was performed as described,15,20 with minor modification。 Protease activities of SMCs and cultured media。Co-Localization of Active Form of Cat S...
08-05-29摘要:【摘要】 Plasmin-catalyzed cleavage of the vascular endothelial growth factor (VEGF)-A isoform VEGF165 results in loss of its carboxyl-terminal heparin-binding domain and significant loss in i...
08-05-29摘要:Virchows Arch B Cell Pathol Incl Mol Pathol 1983, 43:1-16Tribble DL, Barcellos-Hoff MH, Chu BM, Gong EL: Ionizing radiation accelerates aortic lesion formation in fat-fed mice via SOD-inhibitable p...
08-05-29摘要:【摘要】 Vascular remodeling in chronic hypoxic pulmonary hypertension includes marked fibroproliferative changes in the pulmonary artery (PA) adventitia。Selective Depletion of Circulating Fi...
08-05-29摘要:--------------------------------------------------------------------------------Vascular endothelial growth factor (VEGF or VEGF-A) is proangiogenic both in vitro and in vivo。 Cell 1996, 87:1171-1...
08-05-29摘要:--------------------------------------------------------------------------------Hemangioma, also known as infantile hemangioma or hemangioma of infancy, is a relatively common benign tumor。 Cells ...
08-05-29摘要:Arterioscler Thromb Vasc Biol 2001, 21:1998-2003Sorescu GP, Sykes M, Weiss D, Platt MO, Saha A, Hwang J, Boyd N, Boo YC, Vega JD, Taylor WR, Jo H: Bone morphogenic protein 4 produced in endothelial...
08-05-29摘要:Mammary fibroblasts modified to overexpress transforming growth factor-ß。Characterization of the microenvironment that accompanies regression of mammary epithelium after lactation has identif...
08-05-29摘要:ResultsRap1GAP Inhibits Activation of Both Rap1A and Rap1BBoth rap1A and rap1B isoforms are expressed in normal and malignant keratinocytes (SCC)。Rap1GAP Inhibits Proliferation in SCC Cell LinesTo...
08-05-29摘要:The present findings suggest that CSR1 is a potent tumor sup-pressor gene。3 In this study, we identified one of these genes, called cellular stress response 1 (CSR1), a homolog of macrophage scave...
08-05-29摘要:Analysis of Proteins Secreted in the Supernatant (Trichloroacetic Acid Precipitation)Cells (2 x 106) were plated in a 100-mm dish in DMEM containing 10% fetal bovine serum supplemented with 1 mg/m...
08-05-29摘要:2 RhoGTPases cycle between an inactive GDP-bound and an active GTP-bound form。5 Recent work revealed the role of RhoGTPases in hematopoietic cells。11 Cell survival is also regulated by RhoGTPases...
08-05-29摘要:Osteoclast number was comparable in both genotypes, and the expression of bone sialoprotein was similar in tumor-bearing bones of both genotypes, excluding two potential mechanisms of overriding th...
08-05-29摘要:Progenitor cells are frequently detected, but their integration into neovascular structures is variable and often only limited。 Pharmacol Ther 1991, 51:195-216Sunderkotter C, Steinbrink K, Goebele...
08-05-29摘要:Noninvasive Monitoring of Transplants Using Quantitative Computed Tomography (qCT)0 corresponded to nonaerated biological tissue。
08-05-29摘要:3Genetic proof of the critical role of transcription factors in regulating placental development comes from studying mouse gene knockouts。Homeobox genes constitute an important family of transcrip...
08-05-29摘要:Elastic fibers are components of the extracellular matrix and confer resilience。 Elastic fibers are turned over slowly in most adult tissues30 except for the female reproductive organs, where they...
08-05-29摘要:Because v-containing integrins can bind to and/or activate latent TGF-ß。 Our recent observations that vß。5 is up-regulated in scleroderma fibroblasts and that the transient overexpressi...
08-05-29摘要:【摘要】 Calcification of vascular elastin occurs in patients with arteriosclerosis, renal failure, diabetes, and vascular graft implants。Elastin is a major component of the extracellular mat...
08-05-29摘要:【摘要】 BAFF (also known as BLyS), a member of the tumor necrosis factor superfamily, plays a critical role in the maturation and development of B cells。 BAFF has three receptors on B cells,...
08-05-29摘要:pneumonia (PCP) in humans and in surrogate animal species typically occurs in the absence of CD4 T cells, as takes place during acquired immune deficiency syndrome。 However, patients treated with ...
08-05-29摘要:ResultsExpression of Class 4 Semaphorins and SEMA6A mRNA in Cells of the Immune SystemAll RNA preparations were first controlled for the absence of genomic DNA contamination, and cDNA were normaliz...
08-05-29摘要:6-8 Monocyte/macrophages are concentrated around the implantation site and near trophoblasts。Regulation of MCP-1 Protein Expression in Decidual CellsBecause circulating levels of both E2 and proge...
08-05-29摘要:--------------------------------------------------------------------------------Tumor necrosis factor- (TNF-) is a multifunctional cytokine involved in the pathogenesis of multiple disease states i...
08-05-29摘要:--------------------------------------------------------------------------------Copper is an essential co-factor of key metabolic enzymes that participate in a variety of physiological processes, i...
08-05-29摘要:18,21Lobular Distribution of India Ink and Fluorescent-Labeled Ursodeoxycholic Acid (UDCA)India ink was injected into the common bile duct and visualized as previously described18 to determine its ...
08-05-29摘要:Ursodeoxycholic acid (UDCA) is a bile acid widely used for the therapy of cholangiopathies。 Evaluation of Cholangiocyte Functional ActivityThe Protective Effects of UDCA and TUDCA on Vagotomy-Indu...
08-05-29摘要:Yonsei Med J 2004, 45:359-361Tsuboi N, Yoshikai Y, Matsuo S, Kikuchi T, Iwami K, Nagai Y, Takeuchi O, Akira S, Matsuguchi T: Roles of toll-like receptors in C-C chemokine production by renal tubula...
08-05-29摘要:Protocol III: In Vitro Cell Death AssayVentricular cardiomyocytes were isolated from 8-week-old male Sprague-Dawley rats and cultured overnight by the method previously described。 Cardiomyocyte si...
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