摘要：Respiratory function was measured by peak expiratory flow (PEF) in 1974 and 2000 and by forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1) in 1980 and 2000。 Respiratory fu...

摘要：Risk of stroke was analyzed for the entire period and for 0 to 15, 16 to 21, and 22 to 28 years of follow-up using age-adjusted and multiple Cox regression analyses。 Key Words: risk factors stroke...

摘要：Risks were calculated as standardized incidence ratios and compared with individuals without affected siblings。 Results— Ischemic stroke (n=25 630) was associated only with ischemic stroke (n=796...

摘要：the Stroke Registry of Dijon (Inserm and Institut de Veille Sanitaire)。 Key Words: cerebrovascular accident epidemiology incidence risk factors stroke Introduction Stroke medicine is one major asp...

摘要：Abstract Background and Purpose— Cardiac abnormalities occur commonly after subarachnoid hemorrhage (SAH) and may be caused by excessive release of catecholamines from the myocardial sympathetic n...

摘要：the Center for Cardiovascular Disease Prevention, the Donald W。 Reynolds Center for Cardiovascular Research, the Leducq Center for Molecular and Genetic Epidemiology (R。Y。L。Z。, J。L。G。, P。M...

摘要：Abstract Background and Purpose— Carotid intima-media thickness (IMT) reflects generalized atherosclerosis and is predictive of future vascular events。 Carotid Ultrasonography All subjects underw...

摘要：Connective tissue phenotypes for the patients and all family members were assessed by electron microscopic study of skin biopsies。12 Linkage Analysis Three hundred and eighty-three autosomal micro...

摘要：the Division of Cardiovascular Diseases (I。J。K。, K。D。), Mayo Clinic, Rochester, Minn the Human Genetics Center and Institute of Molecular Medicine (E。B。), University of Texas-Houston Health ...

摘要：Abstract Background and Purpose— A 6-point scoring system (ABCD) was described recently for stratifying risk after transient ischemic attack (TIA)。 The frequency of high-risk patients increased w...

摘要：LVD and Risk of Ischemic Stroke LVD of any degree was more frequent in stroke patients (24。 A retrospective analysis from the Study of Left Ventricular Dysfunction (SOLVD) found an increased risk ...

摘要：the Stroke Center, Department of Neurology (D。T。), Neufeld Cardiac Research Institute (M。B。, U。G。, S。B。), and Cardiac Rehabilitation Institute (A。T。, Y。A。, E。Z。F。), Sheba Medical Cen...

摘要：the Department of Clinical Pharmacology (F。A。, R。S。, E。G。), Charite – Universitaetsmedizin Berlin, Berlin, Germany McGill Pharmacoepidemiology Research Unit (S。S。), Division of Clinical Ep...

摘要：Interleukin-10 receptor signaling through the JAK-STAT pathway。

摘要：Previous aspirin use appeared, in univariate analyses, to be associated with greater baseline stroke severity, more severe stroke syndrome, and, in control subjects, worse observed outcome at 6 mon...

摘要：The Local Ethics Committee approved the study and informed consent was obtained。 Local brain haemodynamics and oxygen metabolism in cerebrovascular disease。

摘要：Abstract Background and Purpose— Microglial activation is an important component of the neuroinflammatory response to ischemic stroke。 PK parametric binding potential maps were obtained with the ...

摘要：Cerebral vasoreactivity in Andeans and headache at sea level。 Cerebral autoregulation in subjects adapted and not adapted to high altitude。 Cerebral vasoreactivity in Andeans and headache at sea ...

摘要：Abstract Background and Purpose— Cerebral amyloid angiopathy (CAA) represents -amyloid deposition in the small- and medium-sized vessels of the brain and meninges。 Key Words: aging amyloid cerebr...

摘要：Brain T2-visible hyperintensities are a rather common finding in migraine patients。 Brain stem activation in spontaneous human migraine attacks。 Brainstem activation specific to migraine headache...

摘要：Penumbra was operationally defined as tissue with an admission CBF 25 mL · 100 g–1 · min–1 that was not infarcted on the 5- to 7-day NCCT。 Penumbral tissue had a significantly lower CBF (25。 ...

摘要：J Cereb Blood Flow Metab。 J Cereb Blood Flow Metab。 J Cereb Blood Flow Metab。

摘要：the Stroke Prevention Research Unit, University Department of Clinical Neurology, Radcliffe Infirmary, Oxford, UK。 Abstract Background and Purpose— Some recent studies of noninvasive carotid imag...

摘要：Conclusion— Endovascular cooling improved survival and short-term neurological recovery compared with standard treatment in comatose adult survivors of cardiac arrest。7,8 Endovascular cooling is ...

摘要：Conclusions— Hemostatic activation after AIS appears to be independently associated with clinical outcome in patients treated with rtPA。 Hemostatic markers provide important insight about the pat...

摘要：Abstract Background and Purpose— Determine feasibility and safety of intravenous (IV) versus combined (IV-IA [intra-arterial]) thrombolysis guided by transcranial color-coded duplex sonography (TC...

摘要：the National Cardiovascular Center (T。), Osaka, Japan Tohoku University Graduate School of Medicine (E。 Abstract Background and Purpose— Based on previous studies comparing different recombinant...

摘要：Abstract Background and Purpose— The purpose of this study is to analyze the effect of a modified intraoperative anticoagulation strategy including acetylsalicylic acid (ASA) on complication rates...

摘要：Tissue plasminogen activator for acute ischemic stroke。 Tissue plasminogen activator for acute ischemic stroke in clinical practice: a meta-analysis of safety data。

摘要：Abstract Background and Purpose— In this study we compared risk factors, clinical features, and stroke recurrence in a large series of patients with large subcortical, cortical, or small deep infa...

摘要：Retinal arteriolar emboli were assessed by grading retinal photographs using standardized methods。 Key Words: epidemiology mortality prognosis stroke Introduction Retinal arteriolar emboli can be ...

摘要：The aim of the study was to compare the acute ischemic stroke care and outcomes in centers participating in the Polish National Stroke Prevention and Treatment Registry。 Methods— The World Health...

摘要：) the University Hospital Maastricht, Department of Neurology, Maastricht, The Netherlands (R。 Key Words: ischemia Quality assurance transient ischemic attack Introduction Astraightforward approac...

摘要：Conclusions— Cerebral arterioles in CuZnSOD+/– and CuZnSOD–/– mice undergo marked hypertrophy。 Measurement of Cerebral Arteriolar Pressure and Diameter We measured pressure and diameter in fir...

摘要：the Departments of Neurosurgery (K。K。, M。T。, T。M。, J。K。, T。K。, E。K。) and Geriatric Medicine (T。S。, K。Y。), Graduate School of Medicine, Kobe University, Japan Japan Synchrotron Radia...

摘要：the Department of Medicine, University of Melbourne, and National Stroke Research Institute (N。 Key Words: animal models cerebral infarction pathology stroke, acute Introduction Fluoromisonidazole...

摘要：Conclusions— Apoptosis, and in particular p53, may play an important role in the etiology of vasospasm with relation to SAH, and in this model, vasospasm persisted to 72 hours, despite the fact th...

摘要：Materials and Methods Induction of Intracerebral Hemorrhage All animal procedures were in accordance with our institutional guidelines。 Intracerebral hemorrhage was induced by stereotaxic intrastr...

摘要：Methods— We examined 340-kHz pulsed ultrasound effects in male Wistar rats。 Ultrasound was applied transcranially for 30 minutes on different power levels (1 to 7 W/cm2)。 Temperature was measure...

摘要：4,5 Calpains and cathepsins are 2 families of cysteine proteases that play an important role in stroke-induced cell death。19,20 Cathepsin B antisense transfection reduces inhibition of MMP-9 activ...