摘要：L-Arginine reacts with L-glycine to yield L-ornithine and guanidinoacetate via the enzyme L-arginine:glycine amidinotransferase, principally localized to the kidney and pancreas。 L-Arginine improv...

摘要：The latest available data (for 2001) indicate that the impact factor for Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB) has increased substantially during the past year (from 5。 Vascula...

摘要：Serum nonesterified FFA concentration was measured by using the ACS-ACOD kit (Wako), which had a detection limit of 0。 Serum tumor necrosis factor (TNF)- concentration was determined by ELISA (Bio...

摘要：AbstractTopAbstractIntroductionMethodsResultsDiscussionReferencesObjective— Angiotensin II (AII) has been shown to increase endothelial NAD(P)H oxidase activity, which is a source of superoxide an...

摘要：Cardiovascular Research Center, University of Virginia, Charlottesville, Va To the Editor: In the November 2001 issue of Arteriosclerosis, Thrombosis, and Vascular Biology, Minami et al1 demonstrat...

摘要：AbstractTopAbstractIntroductionMethodsResultsDiscussionReferencesObjective— Coagulation is initiated by the interaction of tissue factor (TF) with plasma coagulation factors VII (FVII) and X (FX)。...

摘要：AbstractTopAbstractIntroductionMethodsResultsDiscussionReferencesObjective— Hepatocyte growth factor/scatter factor (HGF/SF) promotes vascular endothelial growth factor (VEGF) expression and induc...

摘要：e 35, A-6020 Innsbruck, Austria AbstractTopAbstractIntroductionMethodsResultsDiscussionReferencesObjective— Pleiotropic atheroprotective effects of HMG-CoA reductase inhibitors may be mediated on...

摘要：ommittedResults of Clinical Trials of Hormone Therapy and Specialized Estrogen Receptor Modulators (SERMs)The adverse effects of E+P for cardiovascular disease were present across all age groups, i...

摘要：Quantitative trait locus analysis of susceptibility to diet-induced atherosclerosis in recombinant inbred mice。 Quantitative trait loci analysis for the differences in susceptibility to atheroscle...

摘要：AbstractTopAbstractIntroductionMethodsResultsDiscussionReferencesObjective— This study was performed to evaluate the influences of phospholipids and recombinant factor VIIa (rFVIIa) on thrombin ge...

摘要：2 Factor VIIa is also being tested in other clinical settings of uncontrolled bleeding。 Mechanism of factor VIIa-dependent coagulation in hemophilia blood。

摘要：Overexpression of PAI-1 Impairs Obesity in Mice on HFDThe intake of the HFD was somewhat higher for WT than for Tg mice (4。

摘要：Insulin reduced lesion size by 22% to 37% (P0。 Insulin reduced mouse peritoneal macrophage (MPM) lipid peroxides content and superoxide anion release by up to 44% and 62%, respectively (P0。 Blood...

摘要：AbstractTopAbstractIntroductionMethodsResultsDiscussionReferencesObjective— Peroxisome proliferator-activated receptor (PPAR) ligands reduce lesion formation in animal models of atherosclerosis by...

摘要：Response of factor VIII and IX-deficient blood to wild type and high membrane affinity mutant factor VIIa in an in vitro whole blood clotting assay: possible correlation to clinical outcome。 Mecha...

摘要：Methods and Results— Serum PAPP-A levels were determined in asymptomatic hyperlipidemic male subjects (n=64。 Serum lipids and lipoproteins were analyzed by standard analytical procedures, as prev...

摘要：AbstractTopAbstractIntroductionMethodsResultsDiscussionReferencesObjective— The CD40/CD40 ligand pathway mediates inflammatory processes important in atherogenesis and the formation of the intrapl...

摘要：AbstractTopAbstractIntroductionMethodsResultsDiscussionReferencesObjective— A recent study identified a new class of compounds designated as the sterol-regulatory element binding protein (SREBP) c...

摘要：Thrombin GenerationReactant EvolutionSignificance of Intrinsic Factor。Attenuation of Thrombin。SummaryReferencesThe central event of the hemostatic process is the generation of thrombin through th...

摘要：13 Cell CultureRat aortic smooth muscle cells (RASMCs) were isolated from 180 to 200 g male Wistar rats and cultured in DMEM (Life Technologies) with 10% FCS, as previously described,14 and cells w...

摘要：See December 2002, page 2092 Thrombospondins are glycoproteins which constitute a family of at least five, structurally related, multidomain ECM proteins, of which three (THBS-1, -2 and, -5) have b...

摘要：AbstractTopAbstractIntroductionMethodsResultsDiscussionReferencesObjective— L-Arginine serves as a substrate for the formation of NO by the NO synthase (NOS) enzymes。 L-Arginine did not affect th...

摘要：AbstractTopAbstractIntroductionMethodsResultsDiscussionReferencesObjective— Peroxisome proliferator–activated receptors (PPARs) may modulate in vitro the vascular production of vasoactive peptide...

摘要：AbstractTopAbstractIntroductionMethodsResultsDiscussionReferencesObjective— Oxidative stress has been implicated in cellular senescence and vascular aging。 We determined the role and mechanism of...

摘要：AbstractTopAbstractIntroductionMethodsResultsDiscussionReferencesObjective— Cardiac ankyrin repeat protein (CARP) is a transcription factor-related protein that has been studied most extensively i...

摘要：Associations between CAD and all other parameters were first analyzed by simple logistic regression analysis and then by multivariate analysis。ommittedLogistic Regression AnalysisCutoff Point of H...