摘要：ResultsAGI-1067 and AGI-1095 Inhibit LPS-Induced TF Activity in Monocytic Cells and Endothelial CellsIn this study, we investigated the effect of AGI-1067 and AGI-1095 on LPS induction of TF expres...

摘要：Unfractionated heparin+eptifibatide was associated with higher myeloperoxidase levels after percutaneous coronary intervention。 Heparin, but not bivalirudin, fondaparinux, or eptifibatide, increas...

摘要：Preferential sphingosine-1-phosphate enrichment, but sphingomyelin depletion, distinguish normolipidemic small, dense HDL3 from large HDL2。 Enrichment of small HDL in S1P might be mechanistically ...

摘要：【摘要】 Background- ATP-binding cassette transporter A1 (ABCA1) is a key mediator of cholesterol efflux to apoA-I in cholesterol loaded macrophages, a first step of reverse cholesterol transp...

摘要：Incubation of apoA-I with HEK293-ABCA1 cells, but not control cells, led to the formation of heterogeneous-sized, pre-ß。 migrating nascent HDL subpopulations (pre-ß。 When isolated nasce...

摘要：【摘要】 Objective- The purpose of this study was to evaluate the relationships between the peripheral white blood cell (WBC) count, local plaque fibrous cap macrophage density, and the morpho...

摘要：Logistic Regression Analyses of Incident Hypertension, High Cholesterol, and Diabetes Versus Baseline BMI and Waist Circumference in the Total and Healthy-Weight SubsetInteractions between BMI and ...

摘要：Statin-treated children had a less atherogenic lipid profile and did not experience more adverse events, impaired growth and sexual development, or worsened laboratory safety profile when compared ...

摘要：【摘要】 Objective- Adipocyte fatty acid-binding protein (A-FABP) has been shown to be an important player in atherosclerosis in animal models。 This study aims to examine the relationship bet...

摘要：【摘要】 Background- Oxidized phospholipids (OxPL) circulate on apolipoprotein B-100 particles (OxPL/apoB), and primarily on Lp(a) lipoprotein (a) [Lp(a)]。Oxidized phospholipids (OxPL) detect...

摘要：Age, but not CHD, moderated the FMD response to treatment ( P =0。 Study Sample Characteristics by Group (n=100)Age-Related DifferencesThe study sample age range spanned 3 decades, with participant...

摘要：【摘要】 Background- Uridine adenosine tetraphosphate (Up 4 A) was been recently characterized as a potent vasoconstrictor。Isolation And Identification Of Uridine-Adenosine Tetraphosphate Fro...

摘要：【摘要】 Objective- We investigated the effects of angiotensin II (Ang II) on inward rectifier K + (Kir) channels in small-diameter coronary arterial smooth muscle cells (SCASMCs) of control a...

摘要：Tumor necrosis factor- (TNF- ), a pivotal cytokine that regulates ECM metabolism by increasing degradation and decreasing production of arterial collagens, is associated with vulnerable plaques and...

摘要：【摘要】 Objective- Cyclooxygenase-2 (COX-2) and interferon (IFN ) are overexpressed in vascular inflammatory and atherosclerotic lesions。 We postulated that IFN suppresses COX-2 expression a...

摘要：【摘要】 Objective- Activation and proliferation of vascular smooth muscle cells (VSMCs) occur in the venous neointima of vein grafts。 VSMCs in a grafted vein are subjected to mechanical stre...

摘要：【摘要】 Objectives- Basic fibroblast growth factor (bFGF) stimulates vascular smooth muscle cell (SMC) migration。 We determined whether bFGF increases SMC reactive oxygen-species (ROS) and s...

摘要：【摘要】 Objective- Nitrate tolerance is likely attributable to an increased production of reactive oxygen species (ROS) leading to an inhibition of the mitochondrial aldehyde dehydrogenase (A...