摘要：7Osteoprotegerin (OPG) is abundantly produced by osteoblasts at the bone surface and inhibits osteoclast activity, working as a key regulator of bone homeostasis。ResultsEstablishment of Vascular C...

摘要：Univariate and Multivariate Hazard Ratios (HR) for Composite Clinical End Point at Different Follow-Up Durations According to Tertiles of Asymmetric Dimethylarginine (ADMA) and N-Terminal Natriuret...

摘要：Apolipoprotein(a) kringle IV repeat number predicts risk for coronary heart disease。 Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations。

摘要：The present study is a comparative investigation of cellular lipid mobilization and efflux to lipid-free human apoA-I and apoA-I Milano, reconstituted high-density lipoprotein (rHDL) particles cont...

摘要：Phospholipid transfer protein (PLTP) plays an important role in lipoprotein metabolism and atherosclerosis。 10Phospholipid transfer protein (PLTP) circulates bound to HDL and mediates the transfer...

摘要：It remains elusive how CD40 endocytosis or clustering on the cell surface is induced by different forms of CD40 agonist。 This study aims to investigate whether lipid rafts differentially regulate ...

摘要：Circulating Plasma oxLDL MeasurementCirculating plasma oxLDL levels were measured with the enzyme-linked immunosorbent assay Mercodia Oxidized LDL ELISA (Mercodia AB) as previously described。 Enha...

摘要：18Ex Vivo Aorta CultureEx vivo rabbit artery culture models have been already described 19&ndash。 25,26Histology and ImmunohistochemistryElastin fiber integrity was evaluated after orcein staining...

摘要：We previously reported that homocysteine (Hcy) inhibits endothelial cell (EC) growth and promotes vascular smooth muscle cell (VSMC) proliferation。 This study characterized and directly compared H...

摘要：Enriched Membrane Rafts via Association With uPARIn this study, we focus on the function of D5, which is the functional region of HKa in antiangiogenesis and contains an EC binding site。 15 Membra...

摘要：Endothelin-1 (ET-1) and angiotensin II (Ang II) activate common signaling pathways to promote changes in vascular reactivity, remodeling, inflammation, and oxidative stress。 Here we sought to dete...

摘要：Nitroglycerin and pentaerithrityl tetranitrate induce pharmacological preconditioning and protect the endothelium from ischemia and reperfusion damage。 Nitroglycerin induces late preconditioning a...

摘要：Sildenafil increased tissue cGMP levels independently of increases in nitric oxide production, and sildenafil therapy stimulated angiogenesis in ischemic limbs of eNOS &ndash。 10 Sildenafil is a w...

摘要：The goal of this study was to compare vascular function, superoxide levels, and MnSOD protein expression in young (4 to 7 months) and old (22 to 24 months) MnSOD +/+ and MnSOD-deficient (MnSOD +/&n...

摘要：Activation of RhoA and Rho-kinase by serotonin was greater in aorta from males compared with females, but this was not related to greater expression of RhoA or Rho-kinase isoforms (ROCK1 and ROCK2)...

摘要：Arteriogenesis is the major mechanism of vascular growth, which is able to compensate for blood flow deficiency after arterial occlusion。 Endothelial nitric oxide synthase (eNOS) activity is essen...

摘要：Measurement of Adiponectin ConcentrationsSerum adiponectin concentrations in ob/ob mice and diet-induced obese mice were determined by a commercially available enzyme-linked immunosorbent assay (EL...

摘要：Severe Glomerular Hypertrophy and Tubulointerstitial Fibrosis in Subtotal-Nephrectomized Adiponectin-KO MiceSubtotal nephrectomy resulted significant rise in urinary excretion of albumin in KO mice...