摘要：Combinations of HLA and killer cell immunoglobulin–like receptor (KIR) genes have been associated with diseases as diverse as autoimmunity, viral infections, reproductive failure, and now cancer。...

摘要：However, to date no definitive studies have attempted to determine the impact of repeated T cell receptor stimulation on CD4 effector T cell generation。 We have determined that when antigen presen...

摘要：1 Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129 2 Department of Immunobiology, Massachusetts General Hospital and Harvard Medic...

摘要：1 Laboratory of Medicinal Biochemistry, Institute for Medical Research at North Shore–LIJ, Manhasset, NY 11030 2 Laboratory of Chemokine Biology, Institute for Medical Research at North Shore–LIJ...

摘要：1 Laboratory of Cellular and Molecular Biology, National Cancer Institute 2 Laboratory of Mammalian Genes and Development, National Institute of Child Health and Human Development, National Institu...

摘要：1 Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15213 2 Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15213 3 Laboratory of Biomedical Science, No...

摘要：1 Microbiology and Tumor Biology Center, Karolinska Institutet, S-17177 Stockholm, Sweden 2 Strategic Research Center IRIS for studies of Integrative Recognition in the Immune System, Karolinska In...

摘要：1 Laboratory for Immunological Research, Schering-Plough Research Institute, Dardilly 69571, France 2 Division of Immunoregulation, The National Institute for Medical Research, London NW7 1AA, Engl...

摘要：Interleukin (IL)-1 receptor (IL-1R)–associated kinase M (IRAK-M) is only expressed in cells of the myeloid lineage and it inhibits signaling downstream of IL-1R and Toll-like receptors (TLRs)。 Ho...

摘要：1 Institut für Medizinische Immunologie, Charité, Universittsmedizin Berlin, Campus Mitte, 10098 Berlin, Germany 2 Institut für Virologie, Charité, Universittsmedizin Berlin, Campus Mitte, 1009...

摘要：, Cambridge, MA 02139 Although certain chemokines and their receptors guide homeostatic recirculation of T cells and others promote recruitment of activated T cells to inflammatory sites, little is...

摘要：1 Children‘s Hospital, Joint Program in Transfusion Medicine 2 Department of Pathology, Harvard Medical School, Boston, MA 02115 3 Institute of Pathology, University of Oslo, Rikshospitalet Univer...

摘要：1 Department of Neuropharmacology, The Scripps Research Institute, La Jolla, CA 92037 2 Department of Immunology, The Scripps Research Institute, La Jolla, CA 92037 Interferon- (IFN) is important i...

摘要：Here, we report that TGF-1 supports the maintenance of Foxp3 expression, regulatory function, and homeostasis in peripheral CD4+CD25+ regulatory T (T reg) cells, but is not required for their thymi...

摘要：1 Haematopoietic Stem Cell Laboratory, Mater Medical Research Institute, South Brisbane, Queensland 4101, Australia 2 Peter MacCallum Cancer Centre, East Melbourne, Victoria 3002, Australia 3 Depar...

摘要：Hershey Medical Center, Hershey, PA 17033 6 Yale University School of Medicine, New Haven, CT 06520 7 Kaiser Permanente Center for Health Research, Portland, OR 97227 Killer immunoglobulin-like rec...