摘要：Regulatory CD4 T (T reg) cells control immune responses to self-antigens and pathogens。 However, where T reg cells act to curtail effector T cells in vivo and what stage of effector T cell activat...

摘要：SAMP1/YitFc (SAMP) mice develop chronic ileitis similar to human CD。 We used bone marrow chimeras to determine if SAMP ileitis results from a primary immunological defect or from dysregulated muco...

摘要：1 Laboratory of Molecular Genetics and Immunology, The Rockefeller University, New York, NY 10021 2 The Institute for Systems Biology, Seattle, WA 98103 Loss of tolerance in systemic lupus erythema...

摘要：Institute of Parasitology and Biomedicine, Consejo Superior de Investigaciones Cientificas, Granada 18100, Spain Cortistatin is a recently discovered cyclic neuropeptide related to somatostatin tha...

摘要：1 Laboratory of Molecular Immunoregulation and Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Frederick, MD 21702 Interle...

摘要：1 Department of Gene and Cell Medicine, Icahn Research Institute, Mount Sinai School of Medicine, New York, NY 10029 2 Department of Molecular Cell Biology, Free University Medical Center, 1081 HV ...

摘要：1 Laboratory of Molecular Immunology, Laboratory of Cellular Physiology and Immunology, and Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10021 2 Department of Medical a...

摘要：1 Department of Structural Biology, School of Medicine, Stanford University, Stanford, CA 94305 2 Histocompatibility Laboratories, The Anthony Nolan Trust and 3 Department of Haematology, The Royal...

摘要：1 Laboratory of Cellular Physiology and Immunology and Laboratory of Molecular Immunology, Chris Browne Center for Immunology and Immune Diseases, The Rockefeller University, New York, NY 10021 2 D...

摘要：1 Department of Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232 2 The Jackson Laboratory, Bar Harbor, ME 04609 Endoplasmic reticulum (ER)-associated amino...

摘要：Andrew‘s Place, East Melbourne, Victoria 3002, Australia 4 School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, England, UK Little is known regarding the basis for selec...

摘要：Jude Children‘s Research Hospital, Memphis, TN 38105 2 Department of Pathology, University of Tennessee, Memphis, TN 38105 H5N1 influenza viruses transmitted from poultry to humans in Asia cause h...

摘要：However, new studies show that mice lacking FXII are protected against arterial thrombosis (obstructive clot formation) and stroke。 Thus, FXII could be a unique drug target that could be blocked t...

摘要：1 Department of Rheumathology and Clinical Immunology, University of Bern, Inselspital, Berne CH-3010, Switzerland 2 Cancer Research UK Tumor Immunology Group, The Weatherall Institute of Molecular...

摘要：A possible explanation is impaired glutamate uptake。 We have found a highly prevalent polymorphism in the promoter of the glutamate transporter EAAT2 gene that abolishes a putative regulatory site...

摘要：1 Department of Pathology and Department of Medicine, Gastroenterology Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215 Vascular endothelial growth factor...

摘要：1 Howard Hughes Medical Institute and Integrated Department of Immunology, National Jewish Medical and Research Center, 2 Department of Immunology, 3 Department of Medicine, 4 Department of Pharma...

摘要：1 Mucosal Immunity Section, Laboratory of Host Defenses, National Institute of Allergy and Infectious Disease (NIAID), 2 Molecular Immunology and Inflammation Branch, National Institute of Arthrit...

摘要：1 CBR Institute for Biomedical Research and Department of Pathology, Harvard Medical School, Boston, MA 02115 2 Department of Pediatrics, University of Michigan, 3 Department of Internal Medicine, ...

摘要：1 Mucosal Immunology Unit and Immunobiology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, ...

摘要：1 Laboratory of Molecular Genetics and Immunology, The Rockefeller University, New York, NY 10021 2 Renal Electrolyte and Hypertension Division, The University of Pennsylvania, Philadelphia, PA 191...

摘要：Division of Basic Sciences, Fox Chase Cancer Center, Philadelphia, PA 19111 We describe here three CD19– B cell precursor populations in mouse bone marrow identified using 12-color flow cytometry。...

摘要：1 Department of Immunology, Duke University Medical Center, Durham, NC 27710 2 Laboratory of Molecular Genetics and Immunology, The Rockefeller University, New York, NY 10021 CD20 monoclonal antibo...

摘要：are at Department of Medicine, McMaster University, Hamilton, Ontario L8N 3Z5, Canada。 Recent work shows that the mesenteric lymph nodes (MLNs) are the key site for tolerance induction to food pro...

摘要：HIV is evolution gone mad and bad。 Two new studies aim to answer a seemingly simple question—what happens if two genetically identical people are infected with the same strain of HIV In this issu...

摘要：1 Molecular Pathogenesis Program, Skirball Institute of Biomolecular Medicine, 2 Department of Pathology, New York University School of Medicine, New York, NY 10016 Regulatory T (T reg) cells exer...

摘要：Hereditary deficiency of factor XII (FXII), the protease that triggers the intrinsic pathway of coagulation in vitro, is not associated with spontaneous or excessive injury-related bleeding, indica...

摘要：1 Institute of Immunology, Institute of Functional and Applied Anatomy, 2 Department of Visceral and Transplantation Surgery, Hannover Medical School, 30625 Hannover, Germany Oral tolerance induct...

摘要：1 Howard Hughes Medical Institute and Partners AIDS Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129 2 Monogram Biosciences, South San Francisco, CA 94...