摘要：treatment One hundred years ago, lung cancer was a reportable condition and now it accounts for more deaths worldwide from cancer than any other malignant disease。 In 1912, Adler published a book ...

摘要：Hypertension Unit and Sleep Laboratory, Pulmonary Division, Heart Institute (InCor), University of So Paulo, So Paulo, Brazil ABSTRACT Background: Obstructive sleep apnea (OSA) is associated with s...

摘要：Effects of ventilatory mode on sleep quality in critically ill patients。

摘要：First Department of Internal Medicine, Showa University, Tokyo, Japan ABSTRACT Increased carotid intima-media thickness (IMT) and increased serum levels of inflammatory markers, such as C-reactive ...

摘要：METHODS Study Population Patients tested with the QFT-Gold test in the microbiology laboratory of the Policlinico Hospital of Modena between December 1, 2003, and July 30, 2004, were prospectively ...

摘要：Infection with multiple M。 Definitions of Reinfection and Mixed Infection Reinfection was confirmed, according to the gold standard (5), when analysis of serial sputum cultures from a single patie...

摘要：Division of Pulmonary, Allergy Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical School, Pittsburgh, Pennsylvania ABSTRACT As aspects of basic science come to play an...

摘要：Laboratoires de Physiologie and de Pathologie, Facultee de Meedecine Veeteerinaire, Centre de Theerapie Cellulaire et Moleeculaire, Universitee de Lieege, Lieege Laboratoire de Physiologie Animale,...

摘要：Department of Medicine, Divisions of Pulmonary and Critical Care and Allergy and Infectious Diseases, University of Washington, Seattle, Washington Department of Medicine, Division of Rheumatology,...

摘要：Channing Laboratory, Brigham and Women‘s Hospital, Harvard Medical School Department of Anesthesia, Children‘s Hospital and Harvard Medical School Department of Biostatistics, Harvard School of P...

摘要：Effect of deep inhalations after a bronchial methacholine provocation in asthmatic and non-asthmatic subjects。

摘要：Department of Respiratory Diseases, Ghent University Hospital, Ghent, Belgium ABSTRACT Dendritic cells (DCs) are leukocytes that are emerging as chief orchestrators of immune responses。 The crucia...

摘要：Bronchodilator response was measured by spirometry before and 20 minutes after a single dose of inhaled albuterol (2。 Bronchodilator response was calculated as the percent change in FEV1 from base...

摘要：Glucocorticoid receptors (GRs) are specific cytoplasmic transcription factors that mediate the biological actions of corticosteroids (2)。 Isolation of Cytosolic and Nuclear Fractions and Western B...

摘要：Objectives: The aim of this study was to clarify whether activin and its antagonist, follistatin, played a significant role in lung injury and fibrosis。 Methods and Results: In bleomycin (BLM)-tre...

摘要：Clinical Genomic Group, National Heart and Lung Institute, Department of Occupational and Environmental Medicine, Imperial College of Science, Technology and Medicine Department of Radiology, Hamme...

摘要：Departments of Pathology, Medicine Biomedical Informatics Herbert Irving Comprehensive Cancer Center, Columbia University College of Physicians and Surgeons, New York, New York ABSTRACT Rationale: ...

摘要：Microsatellite alterations (MAs) were found in 53% of EBC-DNA and in 10% of WB-DNA loci investigated in patients with NSCLC (p 10eC6)。 Microsatellites are repetitive nucleotide sequences of varyi...

摘要：Department of Pediatrics, Pediatric Heart-Lung Center, Sections of Neonatology Pulmonary and Critical Care Medicine, University of Colorado School of Medicine, Denver, Colorado Department of Pediat...

摘要：Sildenafil preserved alveolar growth and lung angiogenesis, and decreased pulmonary vascular resistance, right ventricular hypertrophy and medial wall thickness。 Sildenafil may have therapeutic po...

摘要：Servicio de Neumologe, Hospital Universitario La Fe Cuidados Intensivos Servicio de Neumologe, Hospital Cleico, Valencia Instituto de Neumologe y Alergia, Hospital Clinic (Red Gira FIS-ISCIII-03/06...

摘要：Conclusions: Hypoxia markedly impairs vascular endothelial function in the systemic circulation in HAPE-S subjects due to a decreased bioavailability of NO。 Effects of Hypoxia on Gas Exchange, Sys...

摘要：Conclusions: Proteolytic enzyme activity in asthma is dependent on the underlying inflammatory phenotype and is differentially regulated with MMP-9 activity a feature of eosinophilic inflammation, ...

摘要：Department of Pulmonary and Critical Care Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio ABSTRACT Bronchial dehiscence after lung transplantatio...

摘要：Azithromycin was introduced at mean 82 months after transplantation。 Azithromycin was commenced at varying time points。 Azithromycin therapy for patients with bronchiolitis obliterans syndrome af...

摘要：Macrophage-activating lipopeptide-2 (MALP-2) is one of the pathogen-associated molecular patterns presently available。

摘要：Key Words: economic analysis oxygen randomized trial Randomized trials have established that patients with resting PaO2 of less than 55 or PaO2 of less than 60 with associated morbidity live longer...

摘要：Departments of Regenerative Medicine and Tissue Engineering, Biochemistry Internal Medicine, National Cardiovascular Center Research Institute, Osaka Second Department of Internal Medicine, Nara Me...

摘要：Within the cultured cells, seven major CD4-expressing TCR-V subset expansions were identified from five of the patients with emphysema。 Conclusion: Severe emphysema is associated with inflammation...

摘要：Key Words: lung cancer nitric oxide nitrotyrosine protein nitration proteomics Nitric oxide (NO) plays a variety of regulatory roles in vivo, including control of vascular tone and host defense。 N...

摘要：Hypoglossus nerve stimulation was as effective as continuous positive airway pressure in reversing inspiratory flow limitation and snoring。 Hypoglossus nerve stimulation had no effect on the rate ...