题 目1:Signaling Pathways Underlying Sensitization of TRPV1 in Inflammatory and Injury Induced Pain
题 目2:Neuroscience Research at the IU School of Medicine
主讲人1:Prof. Gerry Oxford,
Director of Neuroscience Institute, Indiana University School of Medicine.
题 目3:The mechanisms of TNF-α underlying neuropathic pain
主讲人2:刘先国教授
中山大学中山医学院副院长
主持人:刘先国教授
中山大学中山医学院副院长
时 间: 2007年09月10日(星期一)下午15:00时
地 点:中山大学北校区新教学楼205室
简 介:Gerry Oxford is a professor in Pharmacology & Toxicology, Executive Director of Stark Neuroscience Research Institute. Gerry received his Ph.D. from Emory University in 1974. Research in his laboratory is divided into two main themes both of which are focused on the mechanisms by which ion channels control the passage of Na+, K+, and Ca2+ ions across neuronal cell membranes. The first theme deals with the signaling events coupling G-protein coupled receptors and ion channels and how these signals regulate the process of neurotransmitter and hormone secretion. The second theme involves structural and functional analyses of the capsaicin receptor (TRPV1), the key membrane protein which transduces noxious chemical and thermal stimuli into the sensation of pain. We employ patch clamp electrophysiology to study membrane potentials, ion currents, and single channel events combined with biochemistry, molecular mutagenesis, and novel digital image analysis procedures to measure intracellular ions and secretory activity from individual neurons.
欢迎各位师生踊跃参加!
中山大学中山医学院
中山大学医学科学处
2007年09月10日
作者:
2007-9-13