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| 药物名称 | 米格列醇 |
| 药物别名 | 米格列醇、米格尼醇Glyset |
| 英文名称 | Miglitol |
| 说 明 | |
| 功用作用 | Alone as adjunct to diet to treat non-insulin-dependent diabetes. With sulfonylurea when diet plus either miglitol or a sulfonylurea alone do not result in adequate control (effects of sulfonylurea and miglitol are additive). |
| 用法用量 | Tablets Type II diabetes. Individualize dosage. Initial: 25 mg t.i.d. with first bite of each main meal (some may benefit from starting with 25 mg once daily to minimize GI side effects). After 4 to 8 weeks of 25 mg t.i.d. dose, increase dosage to 50 mg t.i.d. for about 3 months. Measure glycosylated hemoglobin; if not satisfactory, increase dose to 100 mg t.i.d. Maintenance: 50 mg t.i.d., up to 100 mg t.i.d. (maximum). |
| 注意事项 | Pregnancy Category: B
Contraindications: Lactation, diabetic ketoacidosis, inflammatory bowel disease, colonic ulceration, partial intestinal obstruction, those predisposed to intestinal obstruction, chronic intestinal diseases associated with marked disorders of digestion or absorption, conditions that may deteriorate due to increased gas formation in the intestine, hypersensitivity to drug. Special Concerns: When given with sulfonylurea or insulin, miglitol causes further decrease in blood sugar and increased risk of hypoglycemia. Safety and efficacy have not been determined in children. |