摘要：AbstractTLRs are conserved pattern recognition receptors that detect motifs of pathogens and host material released during injury。 For unknown reasons, renal TLR2 mRNA is mainly expressed by tubul...

摘要：1Laboratory of Cellular Immunobiology,2Hematology Service, Division of Hematologic Oncology,3Department of Medicine,4Memorial Sloan-Kettering Cancer Center, New York, New York, USA。5Weill Medical ...

摘要：AbstractModified anti-CD3 mAbs are emerging as a possible means of inducing immunologic tolerance in settings including transplantation and autoimmunity such as in type 1 diabetes。 In a trial of a...

摘要：AbstractHuman noncollagenous domain 1 of the 1 chain of type IV collagen , or arresten, is derived from the carboxy terminal of type IV collagen。 In the present study we demonstrate that human 1(I...

摘要：We now report that As2O3 inhibits ligand-induced transcription of the retinoic acid receptor, as well as other nuclear receptors that heterodimerize with the retinoid X receptor (RXR)。 As2O3 did n...

摘要：To determine whether specific lysosomal proteases might influence the outcome of a CD4+ T cell–dependent autoimmune response, we generated mice that lack cathepsin L (Cat L) on the autoimmune diab...

摘要：Ladies and Gentleman, Colleagues, it is a great honor for me to address you today as the President of The Association of American Physicians。 As I stand here, I am acutely aware of the storied 120...

摘要：I first met Bill Kelley in 1970 when I applied for a fellowship in his laboratory at Duke。Bill has been a remarkable visionary leader, always knowing where he wanted to go and how to get there。Pe...

摘要：Thanks also to the officers and councilors of the AAP for selecting me to receive the Kober Medal this year, certainly a signal event in my professional life。 I have been sitting in the audience f...

摘要：Original citation: J。 Clin。 Invest。 115:1785 –1796 (2005)。 doi:10。1172/JCI22849Citation for this corrigendum: J。 Clin。 Invest。 115:2955 (2005)。 doi:10。1172/JCI22849C1The name of one of t...

摘要：Original citation: J。 Clin。 Invest。 115:2330–2340 (2005)。 doi:10。1172/JCI23486Citation for this corrigendum: J。 Clin。 Invest。 115:2955 (2005)。 doi:10。1172/JCI23486C1The name of one of th...