摘要:J Invest Dermatol 2004, 122:201-208Hirakawa S, Fujii S, Kajiya K, Yano K, Detmar M: Vascular endothelial growth factor promotes sensitivity to ultraviolet B-induced cutaneous photodamage。 Microsc ...
08-05-29摘要:1 Vascular injury is one of the most common effects of radiotherapy on normal tissues。 Vascular fibrosis after radiotherapy contributes to severe normal tissue damage and, in some cases, may be a ...
08-05-29摘要:Preeclamptic women displayed increased circulating levels of leukocyte- and platelet-derived microparticles compared with healthy pregnant individuals。 Preeclamptic microparticles induced up-regul...
08-05-29摘要:ResultsReduced Wound-Induced Angiogenesis in EP3 Receptor Knockout Mice50% in control WT mice, and wounds were completely closed after 10 days。 Wound Closure in EP Receptor Knockout MiceFigure 2。...
08-05-29摘要:Human CD34+ Cell-Derived Vasculogenesis and OsteogenesisNext, we performed experiments to characterize the human cells recruited into the fracture sites。Enhancement of Intrinsic Angiogenesis and O...
08-05-29摘要:Multivariate Survival Analysis (Cox Regression Model)Impact of siRNA-Mediated H-REV107-1 Knock-Down on Anchorage-Dependent and Anchorage-Independent Growth in Lung ADC CellsTo test the hypothesis d...
08-05-29摘要:--------------------------------------------------------------------------------Prostate cancer is a heterogeneous disease without well-defined progression。Orthotopic Injection of Prostate Tumor C...
08-05-29摘要:UV also activates the orphan receptor tyrosine kinase and proto-oncogene Erbb2 (HER2/neu)。 In this study, we demonstrate that the UV-induced activation of Erbb2 regulates the response of the skin ...
08-05-29摘要:【摘要】 Matrix metalloproteinase (MMP)-3 is a protease involved in cancer progression and tissue remodeling。 Matrix metalloproteinases (MMPs) were characterized by their ability to degrade e...
08-05-29摘要:Cells were harvested at 3 to 4 days and prepared for gene expression profiling as described in the Materials and Methods。2D Cell CulturesThe OCM1a primary uveal melanoma cell line30 was a generous...
08-05-29摘要:Peroxisomal sequestration may provide an additional point of regulation for HIF signaling in the liver。Hypoxia Does Not Induce Nuclear Localization of HIF-1 in Primary Rat HepatocytesAfter our ass...
08-05-29摘要:Inhibition of PKD of the PCK rat by the use of EGFR tyrosine kinase inhibitors (EKI-785 and EKB-569) resulted in no effect or a worsened PKD as well as no significant effect on the fibrocystic live...
08-05-29摘要:Immunoprecipitation of S100A8 and S100A8/9 ProteinsImmunoprecipitation was performed using protein A/G PLUS agarose immunoprecipitation reagent according to the guidelines of Santa Cruz Biotechnolo...
08-05-29摘要:Hepatitis B virus (HBV) X protein transactivator (HBx) may play a significant role in both processes。HBx Protein Promotes Ang2 Expression in Hepatic Cell Lines and in Stimulated Stellate CellsRT-P...
08-05-29摘要:The receptors Notch1 and Notch2, members of the DSL family of Notch ligands, and the target genes in the Notch-signaling pathway Hes1, Hey1, and Hey2 become strongly up-regulated。 We noted also re...
08-05-29摘要:【摘要】 Peroxiredoxin 6 is an enzyme that detoxifies hydrogen peroxide and various organic peroxides。 Peroxiredoxin 6 overexpression protects keratinocytes from menadione- and UVA-induced ce...
08-05-29摘要:T Cell EnrichmentLymphocytes were isolated from 60 ml of peripheral blood obtained during the orbital decompression surgery。 Lymphocytes were later frozen in RPMI supplemented with 2-mercaptoethan...
08-05-29摘要:Placenta growth factor (PlGF), an angiogenic mediator promoting pathophysiological neovascularization, is expressed during cutaneous wound healing and improves wound closure by enhancing angiogenes...
08-05-29摘要:【摘要】 -1 Antitrypsin (A1AT) is an abundant circulating serpin with a postulated function in the lung of potently inhibiting neutrophil-derived proteases。-----------------------------------...
08-05-29摘要:Endocr Rev 1995, 16:3-34Ghosh P, Dahms NM, Kornfeld S: Mannose 6-phosphate receptors: new twists in the tale。 Science 1988, 239:1134-1137Hille-Rehfeld A: Mannose 6-phosphate receptors in sorting a...
08-05-29摘要:【摘要】 Peroxisome proliferator-activated receptor- co-activator-1 (PGC-1) is a key nuclear receptor co-activator for mitochondrial biogenesis。-----------------------------------------------...
08-05-29摘要:【摘要】 Subcutaneous injection of sodium arsenite (NaAs, 12。5 mg/kg) into BALB/c mice causes acute renal dysfunction characterized by severe hemorrhages, acute tubular necrosis, and cast fo...
08-05-29摘要:Protein extracts of the kidneys (day 7) from the UUO-Tg and the UUO-WT mice were electrophoresed on 15% sodium dodecyl sulfate-polyacrylamide gels and subjected to Western blot analysis using monoc...
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