摘要：9 Inhibition of neutrophil migration into the cornea extended the healing time by 12 to 24 hours。

摘要：7 CellsThe cell line H9c2 was purchased from the American Type Culture Collection, Rockville, MD 。ResultsResident and Infiltrating Inflammatory Cells, but Not Cardiomyocytes, Express COX-2 and NOS...

摘要：【摘要】 We previously reported that angiotensin II type 1 receptor (AT1R) blockade attenuates renal inflammation/fibrogenesis in immune-mediated glomerulonephritis via angiotensin II type 2 r...

摘要：【摘要】 Gain-of-function point mutations in K-ras affect early events in pulmonary bronchioloalveolar carcinoma。 Mutated K-Ras stably expressed in HPL1A accelerated cell growth and induced t...

摘要：Genetic models for the less common subtypes of diaphragmatic hernia have also been characterized。 American Society of Human Genetics (ASHG) 2004, :802Scott DA, Cooper ML, Stankiewicz P, Patel A, P...

摘要：Measurement of Proteinuria and CreatinineAll mice were acclimated in metabolic cages with free access to food and water for collection of 24-hour urine samples。 Proteinuria was normalized for crea...

摘要：【摘要】 The metabolic syndrome is composed of cardiovascular risk factors including increased body mass index/waist circumference, blood pressure, plasma glucose, and triglycerides, as well a...

摘要：J Inflamm 1995, 47:67-75Wallach D, Varfolomeev EE, Malinin NL, Goltsev YV, Kovalenko AV, Boldin MP: Tumor necrosis factor receptor and Fas signaling mechanisms。 FASEB J 2005, 19:1637-1645Chainy GB...

摘要：ResultsTrophoblasts Induce Apoptosis in Arterial Media SMCs in SituIn previous experiments we have shown that the presence of trophoblasts in spiral arteries initiates endothelial cell apoptosis。 ...

摘要：Effect of E2 on the Body Weight, Uterine Weight, Reendothelialization, and Circulating EPC in Ovariectomized Process in OvariectomizedFgf2C/C Grafted with Fgf2+/+ BM or Fgf2+/+ Grafted with Fgf2C/C...

摘要：【摘要】 Myosin VI is an actin motor that moves to the minus end of the polarized actin filament, a direction opposite to all other characterized myosins。 Using expression microarrays, we ide...

摘要：【摘要】 4Stimulation of Fas-mediated apoptosis has been promoted as a potential therapy for many cancers, including cholangiocarcinoma。 We have previously reported that Fas-resistant, but no...

摘要：Number of Mammary Epithelial Histotypes Identified and Evaluated for Proliferative and Apoptotic ActivitiesFigure 1。Transgenic Mice Displayed Altered Apoptotic Activity in Both Age Groups16 weeks,...

摘要：【摘要】 MicroRNAs are small noncoding 18- to 24-nt RNAs that are predicted to regulate expression of as many as 30% of protein-encoding genes。 Dicer, an RNase III endonuclease, is an essenti...

摘要：--------------------------------------------------------------------------------Caveolin-1 (Cav-1) is the principal structural protein of caveolae, 50- to 100-nm omega-shaped membrane invaginations...

摘要：Biophys J 2005, 88:62-75Galle J, Aust G, Schaller G, Beyer T, Drasdo D: Individual cell-based models of the spatio-temporal organisation of multicellular systems。hme S: Individual-based approaches...

摘要：【摘要】 Platelet-derived growth factor (PDGF) stimulates tumor growth and progression by affecting tumor and stromal cells。 In the HaCaT skin carcinogenesis model, transfection of immortal n...

摘要：【摘要】 Angiogenesis is a complex process whereby new blood vessels form from pre-existing vasculature in response to proangiogenic factors such as basic fibroblast growth factor (bFGF) and t...

摘要：Tumor cell lines used included B16 (syngeneic with C57BL/6 H-2b, melanoma), Line1 (syngeneic with BALB/c mice H-2d, lung carcinoma), EMT6 (syngeneic with BALB/c mice, mammary carcinoma), K1735。Res...

摘要：Ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1) is exclusively expressed in neurons, testis, ovary, and placenta, each of which has unique biological activities。---------------------------------...

摘要：【摘要】 We previously showed that Trypanosoma cruzi acute infection induced infertility in a great proportion of female mice, which resulted from a defect taking place before implantation。 I...

摘要：45 Mast cell-deficient KitW-sh/W-sh mice on the C57BL/6 background were generously provided by Dr。Preparation of Bone Marrow-Derived, Cultured Mast Cells and Local Mast Cell Engraftment of Mast Ce...

摘要：【摘要】 Schistosoma mansoni egg-induced inflammation is accompanied by TH2 cell polarization and development of fibrotic granulomas in host tissue。 The interleukin (IL)-4 receptor (IL-4R), ...

摘要：Quantitation of PGN-Containing CellsThe number of PGN-containing cells in the parenchyma and infiltrates of brain tissue derived from marmoset and rhesus monkeys were quantitated by two independent...

摘要：【摘要】 Flagellin, the primary component of bacterial flagella, is a potent activator of toll-like receptor 5 (TLR5) signaling and is a major proinflammatory determinant of enteropathogenic S...

摘要：4,5 Morphine enhances HIV replication in chronically infected promonocytes co-cultured with human brain cells。ReagentsMorphine sulfate was obtained from Elkins-Sinn, Inc。Morphine Abrupt Withdrawa...

摘要：Reduction of Tyrp1 Protein Following Treatment with 4-TBPReduction in Tyrp1 expression following exposure to 4-TBP and subsequent to down-regulation of MITF was confirmed。 Oncogene 2003, 22:3035-3...

摘要：--------------------------------------------------------------------------------Methylation of promoter CpG islands (CGIs) causes silencing of their downstream genes,1,2 and that of tumor-suppresso...

摘要：【摘要】 We have recently shown that insulin-like growth factor-binding protein (IGFBP)-5 is overexpressed in idiopathic pulmonary fibrosis lung tissues and increases collagen and fibronectin ...

摘要：【摘要】 Heme oxygenase (HO) represents an intrinsic anti-inflammatory system based on its ability to regulate leukocyte function and inhibit expression of proinflammatory cytokines。 Gene 200...

摘要：Nat Med 1996, 2:287-292Lazar MH, Christensen PJ, Du M, Yu B, Subbotina NM, Hanson KE, Hansen JM, White ES, Simon RH, Sisson TH: Plasminogen activator inhibitor-1 impairs alveolar epithelial repair ...

摘要：11Heat shock proteins (HSPs) are a group of highly conserved proteins originally identified as proteins that are up-regulated in response to elevated temperatures。Effects on Radiation-Induced Glan...