摘要:J Allergy Clin Immunol 2003, 112:15-22Asako H, Kurose I, Wolf R, DeFrees S, Zheng ZL, Phillips ML, Paulson JC, Granger DN: Role of H1 receptors and P-selectin in histamine-induced leukocyte rolling...
08-05-29摘要:Isolation of Mitochondria and Mitochondrial FractionsCultured MECs were resuspended in ice-cold RSB buffer (10 mmol/L NaCl, 1。Immunohistochemistry for Transgene ExpressionEight- to 10-week-old Trx...
08-05-29摘要:【摘要】 Natural killer T (NKT) cells have recently been implicated in atherogenesis, primarily for their ability to recognize and respond to lipid antigens。Natural killer T (NKT) cells are a...
08-05-29摘要:Local Tumor Growth and Dissemination Pattern in Animals Bearing Tumors Derived from OCMI-Implanted Human Colorectal Cancer Cell LinesThe three cell lines gave rise to poorly differentiated adenocar...
08-05-29摘要:7Hyaluronan (HA) is a major constituent of ECM linking proteoglycans and other binding molecules into macromolecular aggregates。Generation of Has2 Transgenic Animal and Backcross with Mammary Tumo...
08-05-29摘要:7Fibroblasts surrounding and within invasive breast carcinomas 。Identification of Human NAFs in Xenografts by 5-Chloromethylfluorescein Diacetate (CMFDA) LabelingLabeling of NAFs with CellTracker ...
08-05-29摘要:Adhesion Assays to ECM ProteinsSolid-phase assays in which 96-well tissue culture plates were coated with FN, Col I, and VN were performed as described earlier。 Protein detection was performed usi...
08-05-29摘要:--------------------------------------------------------------------------------Glucocorticoids (GCs) belong to a class of steroid hormones that are synthesized by the adrenal gland and released in...
08-05-29摘要:Macrophages from GM+/+ mice showed numerous hallmarks of alternatively activated macrophages: higher numbers of intracellular cryptococci, YM1 crystals, and induction of CCL17。Granulocyte macropha...
08-05-29摘要:【摘要】 When intraperitoneally injected into Swiss mice, Clostridium sordellii lethal toxin reproduces the fatal toxic shock syndrome observed in humans and animals after natural infection。-...
08-05-29摘要:Calcitonin (10C10 mol/L) abrogated the stimulating effect of 10 ng/ml RANKL or 10C9 mol/L prednisolone。16Calcitonin (CT), a peptide hormone secreted in response to hypercalcemia, has the dual effe...
08-05-29摘要:all antibodies from the American Type Culture Collection, Manassas, VA) as primary antibodies and peroxidase-linked sheep anti-rat IgG F(ab‘)2 (Amersham Pharmacia, Freiburg, Germany) as secondary ...
08-05-29摘要:ResultsTSLP Transgenic Mice Develop Mixed Cryoglobulinemia and Hepatitis Reminiscent of Human Chronic Hepatitis CSera from 95% of TSLP transgenic animals and 100% of TSLP/FcRIIbC/C animals containe...
08-05-29摘要:Erythrocytes isolated from the model showed marked fragility and the externalization of phosphatidylserine (PS) on the outer leaflet of the membrane and were frequently engulfed by Kupffer cells/ma...
08-05-29摘要:【摘要】 Epithelial cell migration is a critical event in gastrointestinal mucosal wound healing and is dependent on actin cytoskeletal reorganization。Annexin 2 is a calcium-dependent phospho...
08-05-29摘要:Hypermethylation of the Ras association domain family 1 A (RASSF1A) gene was found in human placentas from all three trimesters of pregnancy but was absent in other fetal tissues。 Hypermethylation...
08-05-29摘要:17,18 Cathepsin G is a serine protease that makes up approximately 20% of the azurophilic granule proteins of neutrophils。19 Cathepsin G has many important roles in neutrophil function during infl...
08-05-29摘要:【摘要】 Lactadherin is a secreted extracellular matrix protein expressed in phagocytes and contributes to the removal of apoptotic cells。 We examined lactadherin expression in brain sections...
08-05-29摘要:Am J Pathol 2001, 159:1031-1043Hung TH, Skepper JN, Charnock-Jones DS, Burton GJ: Hypoxia-reoxygenation: a potent inducer of apoptotic changes in the human placenta and possible etiological factor ...
08-05-29摘要:Functional Characterization of Mouse LAT3cRNA for mouse LAT3 was obtained by in vitro transcription using SP6 RNA polymerase from the mouse LAT3 cDNA in plasmid pSPORT6 linearized with NotI。mRNA a...
08-05-29摘要:Immunohistochemistry for Detecting Bone Marrow-Derived CellsImmunohistochemistry was performed on Bouin。ResultsBone Marrow-Derived Cells Were Detected in the Live Testicular Tissue 10 to 12 Weeks ...
08-05-29摘要:【摘要】 Granulomatous experimental autoimmune thyroiditis (G-EAT) is induced by mouse thyroglobulin-sensitized splenocytes activated in vitro with mouse thyroglobulin and interleukin-12。 Our...
08-05-29摘要:【摘要】 Mitochondrial toxicity limits nucleoside reverse transcriptase inhibitors (NRTIs) for acquired immune deficiency syndrome。 NRTI triphosphates, the active moieties, inhibit human immu...
08-05-29摘要:【摘要】 We investigated the pathogenic roles of CC chemokine ligand (CCL)3 and its receptors, CC chemokine receptor (CCR)1 and CCR5, in bleomycin (BLM)-induced pulmonary fibrosis (PF)。 Intra...
08-05-29摘要:【摘要】 The transcription factor aryl hydrocarbon receptor (AhR) plays an important role in the response to environmental pollutants。 To investigate the role of AhR in acute lung inflammatio...
08-05-29摘要:【摘要】 In polycystic kidney disease (PKD), erythropoietin (EPO) production and interstitial vascularization are increased compared with other kidney diseases。 EPO and several angiogenic fac...
08-05-29摘要:【摘要】 Macrophages have been suggested to be beneficial for myocardial wound healing。 Macrophages have been shown to play a central role in wound healing, demonstrating several activities s...
08-05-29摘要:Atherosclerosis 2004, 177:353-360Wilson WR, Schwalbe EC, Jones JL, Bell PR, Thompson MM: Matrix metalloproteinase 8 (neutrophil collagenase) in the pathogenesis of abdominal aortic aneurysm。 Circu...
08-05-29摘要:Reactive oxygen species (ROS), particularly superoxide anion, are well known to inhibit NO, and therefore the mechanisms by which endothelium regulates production of ROS are also of high interest。...
08-05-29摘要:Murine toxicology studies are also fundamental because they identify safe starting doses for phase I protocols。 【关键词】 evaluate conventional therapeutic strategies History of Tumo...
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