摘要:Integrins are able to mediate the outgrowth of newly formed blood vessels。 Integrin 5-inhibiting small molecules significantly blocked the outgrowth of new lymphatic vessels into the cornea in a d...
08-05-29摘要:Immunofluorescent Co-Localization of MPO and HK on Endothelial CellsHUVECs were grown to 80% confluence on 0。ResultsIdentification of CK1 and CK9 as Endothelial MPO-Binding ProteinsTo identify end...
08-05-29摘要:Eighty skin biopsies from 40 patients with previously treated primary breast cancer were taken from irradiated skin and corresponding contralateral unirradiated control areas 2 to 8 weeks, 11 to 14...
08-05-29摘要:Antibodies Used for ImmunohistochemistryResultsEndothelial Gene Expression Profiling in AtherosclerosisThe atherosclerotic plaques were classified according to Virmani and colleagues。Differential ...
08-05-29摘要:【摘要】 Interleukin (IL)-6 acts via a receptor complex consisting of the cognate IL-6 receptor (IL-6R) or the soluble IL-6 receptor (sIL-6R) and glycoprotein 130 (gp130)。 Here, we investigat...
08-05-29摘要:Human THP-1 monocytes and peripheral blood mononuclear cells were preincubated with acetylated low-density lipoprotein and cholesterol to form foam cells, which were then treated with apolipoprotei...
08-05-29摘要:【摘要】 The c-Jun NH2-terminal kinase (JNK) signal transduction pathway plays important roles in cellular processes and stress。---------------------------------------------------------------...
08-05-29摘要:, which is known to influence cell growth control, apoptosis, and cellular response to DNA damage, has been verified to be specific in hepatocellular carcinoma and consistent with the degree of mal...
08-05-29摘要:Hyaluronan oligosaccharides have been shown to inhibit several tumor cell types via disruption of receptor-hyaluronan interaction。 Hyaluronan octasaccharides significantly inhibited cell viability...
08-05-29摘要:Gene expression was measured using U133-X3P Human GeneChip oligo-based microarrays (Affymetrix)。 Affymetrix CEL files are available online at Gene Expression Omnibus (accession number GSE7377。 Th...
08-05-29摘要:Molecular profiles for each grade of PanIN have been defined with activating mutations in the KRAS proto-oncogene thought to be early events in the development of PanIN-1 lesions。 Acinar-ductal me...
08-05-29摘要:【摘要】 TAR DNA-binding protein 43 (TDP-43) is a major pathological protein of sporadic and familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions (FTLD-U...
08-05-29摘要:25MSC TransplantationBefore transplantation, cultured MSCs were released from the dishes with 0。26,27Transplantation and Detection of MSCs in the Inner Ear TissueTo improve the hearing recovery of...
08-05-29摘要:Here, we show that overexpression of the cytotoxic T cell (CT) GalNAc transferase (Galgt2) is effective in inhibiting the development of muscle pathology in the dyW mouse model of MDC1A, much as we...
08-05-29摘要:【关键词】 triggers myd-dependent tlr/-independent inflammatory responses Materials and MethodsMouse Model of Cold-Induced Cortical InjuryTo induce aseptic brain tissue damage, a well-establishe...
08-05-29摘要:FEBS Lett 1993, 317:207-210Higuchi K, Naiki H, Kitagawa K, Kitado H, Kogihshi K, Matsushita T, Takeda T: Apolipoprotein A-II gene and development of amyloidosis and senescence in a congenic strain ...
08-05-29摘要:Sarcoglycans are transmembrane components of the dystrophin-glycoprotein complex, which links the cytoskeleton to the extracellular matrix。71 【参考文献】 Tsubata S, Bowles KR, Vatta M, Z...
08-05-29摘要:【摘要】 Cells undergo apoptosis in development, tissue homeostasis, and disease and are subsequently cleared by professional and nonprofessional phagocytes。 Apoptotic cells are rapidly engul...
08-05-29摘要:【摘要】 Neutral sphingomyelinase SMPD3 (nSMase2), a sphingomyelin phosphodiesterase, resides in the Golgi apparatus and is ubiquitously expressed。 Gene ablation of smpd3 causes a generalized...
08-05-29摘要:【摘要】 Glomerular charge selectivity has been attributed to anionic heparan sulfate proteoglycans (HSPGs) in the glomerular basement membrane (GBM)。 Glomerular capillary loops were photogra...
08-05-29摘要:【摘要】 Adenoid cystic carcinoma is a frequently occurring malignant salivary gland neoplasm。 We studied the induction of protease activity by the laminin-derived peptide, SIKVAV, in cells (...
08-05-29摘要:ResultsStimulation of -SMA and SM22 Expression in FibroblastsThe identification of myofibroblasts was performed through immunofluorescent labeling of -SMA (Figure 1A) 。Osteogenic ResponsesTo appra...
08-05-29摘要:【摘要】 Live-attenuated Plasmodium liver stages remain the only experimental model that confers complete sterile protection against malaria。 Irradiation-attenuated Plasmodium parasites media...
08-05-29摘要:--------------------------------------------------------------------------------Autoimmune diabetes results from a systemic breakdown in central and peripheral mechanisms of tolerance, leading to e...
08-05-29摘要:Here, we report that although Fas expression on splenocytes and hepatocytes is up-regulated by CLP and is inhibited by in vivo short interfering RNA, FasL as well as the frequency of CD8+ T cells a...
08-05-29摘要:【摘要】 Fas/Fas ligand (Fas-L) engagement, a potent inducer of apoptosis, is also important for cellular activation, regulation of effector and chemotactic activity, and secretion of chemokin...
08-05-29摘要:【摘要】 Vascular endothelial growth factor-A (VEGF-A) has recently been recognized as an important neuroprotectant in the central nervous system。---------------------------------------------...
08-05-29摘要:11 Ephrin-B1 is frequently overexpressed in gastrointestinal tumors, especially in poorly differentiated invasive tumor cells。Ephrin-Bs are tyrosine phosphorylated via Src family kinases in respon...
08-05-29摘要:Skin Reconstruction from Normal Human Keratinocytes and HI Patients。 Keratinocytes with Normal FibroblastsG and the other harbored heterozygous mutations: p。 Expression of ABCA12 and TGase1 in de...
08-05-29摘要:ResultsTranscriptome of Psoriatic SkinTo better understand molecular dysregulation within psoriatic tissue, we were first interested in defining the transcriptional changes occurring in lesional sk...
08-05-29摘要:【摘要】 The predominant testicular gap junctional protein connexin43 (cx43) is located between neighboring Sertoli cells (SCs) and between SCs and germ cells。--------------------------------...
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