摘要:Multivariable Logistic Regression Analysis of Polymorphisms Related to Atherothrombotic Infarction, Intracerebral Hemorrhage, or Subarachnoid Hemorrhage in Dominant, Recessive, or Additive (1 or 2)...
08-12-28摘要:Genotyping of Six SNPs in the FXIII A-subunit GeneThe twins were genotyped for a common promoter and all common nonsynonymous coding polymorphisms in the FXIII A-subunit gene (references for genome...
08-12-28摘要:ResultsPAF-AH Secretion From Activated PlateletsThrombin induced a dose- and time-dependent secretion of the enzyme, with a maximum of 716±。 Platelets are positively stained with the monoclo...
08-12-28摘要:【摘要】 Objective- To evaluate the role of factor (F) VIII in children with non-cancer related venous thrombosis (DVT), post-thrombotic syndrome (PTS) or recurrent DVT。Methods and Results- F...
08-12-28摘要:Gene sequence variations of CYP3A4 have been suggested to contribute to clopidogrel responsiveness。 Genetic contribution to variable human CYP3A-mediated metabolism。 Contribution of hepatic cytoc...
08-12-28摘要:Temperature gradient between culprit and nonculprit segments was observed only when transient blood flow interruption occurred during thermography。 Temperature was measured during an automatic pul...
08-12-28摘要:Conclusions- Childhood CRP values predict weakly but significantly adult CRP, and this association is independent of other metabolic risk factors。 Childhood serum samples were taken in 1980 and st...
08-12-28摘要:Maternal age ( P =0。 Partial Correlation Coefficients, Adjusted for Sex, Between IMT and Maternal Nutrient Intake in Early and Late PregnancyTwenty-four mothers reported severe nausea during pregn...
08-12-28摘要:Hypoxia increased the mRNA and protein levels of adipocyte differentiation-related protein (ADRP)。 Hypoxia decreased the expression of enzymes involved in ß。ResultsHypoxic Treatment of Human...
08-12-28摘要:【摘要】 Objective- Activation of transcription factor NF- B is an important step in the development of vascular damage, because it controls inducible genes, including many inflammatory mediat...
08-12-28摘要:Conclusion- Bone marrow-derived CCR5 favors the development of an inflammatory and collagen-poor plaque phenotype in association with decreased macrophage-derived IL-10 and enhanced T cell-derived ...
08-12-28摘要:Atherosclerosis in the aortas and aortic root sections were quantified using Image Pro Plus version 5。Prevention of AtherosclerosisAtherosclerosis was quantified using 2 independent methods 1 year...
08-12-28摘要:7Fibroblast growth factors exert their biological effects by interacting with and activating a family of 4 fibroblast growth factor receptors (FGFR-1 to -4) with protein tyrosine kinase activity。 ...
08-12-28摘要:Unstable segments contained a disrupted fibrous cap or surface thrombus or hemorrhage。Genes from the GeneChip analysis were selected for confirmation of differential expression based both on the m...
08-12-28摘要:Genes, environment and coronary artery disease。Clee SM, Zwinderman AH, Enghert JC, Zwarts KY, Molhuizen HOF, Roomp K, Jukema W, van Wijland M, vanDam M, Hudson TJ, Brooks-Wilson A, Genest J Jr, Ka...
08-12-28摘要:Conclusions- Hepatic ABCA1 has a critical role for HDL catabolism in plasma and for HDL selective CE uptake by the liver。 Hepatic HDL selective CE uptake (ie, the difference between [ 3 H]CEt and ...
08-12-28摘要:Lipoprotein Cholesterol Distribution and LDL SizeLDL particle size was measured in each of the treatment groups because this variable has been positively associated with hepatic secretion rates of ...
08-12-28摘要:【摘要】 Objectives- During inflammation, the serum amyloid A (SAA) content of HDL increases, whereas apolipoprotein A-I (apoA-I) and paraoxonase-1 (PON-1) decrease。 It remains unclear whethe...
08-12-28摘要:Matrix metalloproteinases-9 and 2, and serum elastase activity are associated with systolic hypertension and arterial stiffness。 Matrix metalloproteinase-9 influences large artery stiffness throug...
08-12-28摘要:ResultsLevels of mRNA Expression in Control and Stenotic ValvesRT-PCR revealed that cathepsins S and K and cystatin C were produced locally in both stenotic and control aortic valves。Degradation o...
08-12-28摘要:Materials and MethodsMouse Aortic Endothelial Cell Culture and Shear Stress StudiesMouse aortic endothelial cells (MAEC) obtained from the thoracic aortas of C57/BL6 mice were isolated, cultured in...
08-12-28摘要:【摘要】 Objective- Proliferation of vascular smooth muscle cells (VSMCs) contributes to restenosis after coronary intervention。 We have shown previously that increased expression of plasmino...
08-12-28摘要:【摘要】 Objective- Vascular endothelial growth factor (VEGF) exerts many of its effects by stimulating endothelial calcium influx, but little is known about channels mediating VEGF-induced ca...
08-12-28摘要:【摘要】 Objective- Endothelial progenitor cells (EPCs) contribute to postnatal neovascularization and are therefore of great interest for autologous cell therapies to treat ischemic vascular ...
08-12-28摘要:Vascular NO formation was analyzed using electron paramagnetic resonance (EPR), expression of NADPH oxidase subunits, the endothelial NO synthase (eNOS), the soluble guanylyl cyclase (sGC), as well...
08-12-28摘要:Systemic Characteristics and Myocardial Microvascular Function in Normal, Hypertension (HT), and HT+Antioxidants PigsMicrovascular RemodelingThe spatial density of microvessels (500 µ。Oxidati...
08-12-28摘要:【摘要】 Precise modulation of thrombin activity throughout the hemostatic response is essential for efficient cessation of bleeding while preventing inappropriate clot growth or dissemination...
08-12-28摘要:【摘要】 Thrombosis occurs in a dynamic rheological field that constantly changes as the thrombus grows to occlusive dimensions。Thrombosis occurs in a dynamic rheological field where flow con...
08-12-28摘要:【摘要】 Background- Over the past 10 to 15 years, calcific aortic valve disease, which includes aortic sclerosis and aortic stenosis, has come to be recognized as an active process, based on:...
08-12-28摘要:【摘要】 Transforming growth factor-ß。 (TGF-ß。) superfamily members, TGF-ß。 In atherosclerosis, TGF-ß。
08-12-28摘要:Macrophages in lesions have been shown to express 6 structurally different scavenger receptors for uptake of modified forms of low-density lipoproteins (LDLs) that promote the cellular accumulation...
08-12-28摘要:【摘要】 It is well known that humans with diabetes have more atherosclerosis and its complications。 Although recent data show that improved glycemic control reduces arterial disease in type ...
08-12-28