摘要:A, Platelets were stimulated with Amyloid-ß。Amyloid Proteins Activate Platelets in Part Through p38 MAPK, COX-1, and CD36Because amyloid proteins are known to bind to scavenger receptors, 28 ...
08-12-28摘要:Conclusion- Endothelial fibrinolytic capacity, as measured by stimulated t-PA release, predicts the future risk of adverse cardiovascular events in patients with coronary heart disease。ResultsEndo...
08-12-28摘要:【摘要】 Objective- Although serum amyloid A (SAA) is a useful biomarker of coronary artery disease (CAD), its direct role in procoagulation is obscure。 This study investigates the impact of ...
08-12-28摘要:【摘要】 Objective- We examined the Type A behavior across developmental periods as a predictor of adult carotid artery intima-media thickness (IMT)。Methods and Results- In this prospective c...
08-12-28摘要:B, Specific endothelial cell ethidium fluorescence was measured on the luminal side of the internal elastic lamina only and expressed in arbitrary units。
08-12-28摘要:Enhanced atherogenesis was associated with enhanced activation of both B and T lymphocytes and with arterial inflammation involving endothelial cell activation, monocyte recruitment, and accumulati...
08-12-28摘要:Preparation and acLDL-Loading of Human Primary MacrophagesHuman primary macrophages were differentiated from buffy coat mononuclear cells using granulocyte-macrophage colony stimulating factor (GM-...
08-12-28摘要:【摘要】 Objectives- Apolipoprotein E (apoE) exerts antiatherogenic effects but precise mechanisms remain unclear。 We here investigated the effect of apoE on intracellular signaling by interl...
08-12-28摘要:【摘要】 Objective- The purpose of this study was to understand the interactions of apoA-I with cells expressing ABCA1。C of 125 I-WT apoA-I to the cells and specifically to ABCA1, as determin...
08-12-28摘要:Methods and Results- Cholesterol loading by incubation with cholesterol-chelated methyl-ß。 Cholesterol loading decreased both the cellular levels of GTP-bound active RhoA and the phosphorylat...
08-12-28摘要:【摘要】 Objectives- It is believed that adipose tissue acts as an endocrine organ by producing inflammatory mediators and thereby contributes to the increased cardiovascular risk seen in obes...
08-12-28摘要:Ryanodine also restored peak NO production in 1 µ。 Removal of the remaining FKBP12 with 1 µ。
08-12-28摘要:【摘要】 Objective- Two types of endothelial progenitor cells (EPCs), early EPCs and late EPCs (also called endothelial outgrowth cells ), were described in vitro previously。 In this report, ...
08-12-28摘要:【摘要】 Objectives- Ephrin ligands and Eph receptors are signaling molecules that are differentially expressed on arteries and veins during development。 We examined whether Eph-B4, a venous ...
08-12-28摘要:【摘要】 Objective- Histamine increases endothelial nitric oxide (NO) production as an endothelium-dependent vasodilator, which acts as a vasoconstrictor in atherosclerotic coronary arteries。...
08-12-28摘要:【摘要】 Objective- The role of inducible cAMP early repressor (ICER), a transcriptional repressor, in the vascular remodeling process has not been determined。Inducible cAMP early repressor (...
08-12-28摘要:Retinoids, especially all-trans retinoid acid, are known to regulate many processes activated at sites of vascular injury, including modulation of SMC phenotype and inhibition of SMC proliferation。...
08-12-28摘要:【摘要】 Objective- The purpose of this study was to evaluate the role of coactivator histone acetyltransferases (HATs) p300 and SRC-1 in angiotensin II (Ang II)-induced interleukin-6 (IL-6) g...
08-12-28摘要:【摘要】 Objectives- Acyclic retinoid (ACR) is a synthetic retinoid with a high safety profile that has been pursued with high expectations for therapeutic use in prevention (recurrence) and t...
08-12-28摘要:Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse。 Steroid receptor coactivator-3 is required for inhibition of neointim...
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