摘要：ResultsEfficient GFP Expression in Platelets Using LentiLox Vector Harboring GPIb Promoter In VivoWe first substituted the CMV promoter of pLL3。Efficiency of Lentiviral shRNA for Silencing of Targ...

摘要：After PCI all patients were observed at the outpatient clinic。 After incubation, tubes containing the clots were connected to a reservoir of a buffer (0。 Characteristics of Patients With and With...

摘要：The purpose of this study was to investigate the effects of plasminogen activator inhibitor-1 (PAI-1) gene (SERPINE1) single nucleotide polymorphisms (SNPs) on the risk of myocardial infarction (MI...

摘要：Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults。 Carotid intimal-medial thickness is related to cardiovascular risk factors measured...

摘要：ResultsEffect of Hypolipidemic Therapy on Serum Lipid ProfileAs shown in supplemental Table I (available online at http://atvb。Effect of Hypolipidemic Therapy on Lipoprotein SubclassesType IV dysl...

摘要：Maternal hypercholesterolemia is associated with a higher incidence and faster progression of atherosclerotic lesions in neonatal offspring。 Maternal blood samples were acquired before pregnancy a...

摘要：Familial combined hyperlipidemia (FCHL) characterized by high serum total cholesterol and/or triglycerides (TGs) is a common dyslipidemia predisposing to coronary artery disease (CAD)。 Recently, t...

摘要：Activity Neutralization on Fatty Streak Constitution in Placebo- or E2-Treated ApoE &ndash。 Activity Neutralization on Lesion Composition and Cytokine ProductionAs previously reported, neutralizin...

摘要：【关键词】 cytomegalovirus atherosclerosis inflammation immunopathology coronary heart disease IntroductionChronic inflammatory processes in the vascular wall are crucial for initiation and perp...

摘要：In our previous studies that examined in vivo activities of oncostatin M (OM) in upregulation of hepatic LDL receptor (LDLR) expression, we observed reductions of LDL-cholesterol and triglyceride (...

摘要：Ubiquitin-mediated protein degradation plays a crucial role in various cellular processes, including signal transduction, cell differentiation, and stress response。 5 Ubiquitinated I B- is also ab...

摘要：There was an increase in hepatic sterol synthesis and markedly increased fecal loss of neutral sterols。 Hepatic mRNA levels of 3-hydroxy-3-methylglutaryl (HMG) coenzyme A (CoA) reductase, Srebp-1c...

摘要：Pressure signals were digitized using a Powerlab (AD, Instruments GmbH) and were continuously recorded using Chart for Windows (Version 4。 Antagonism of in vivo and ex vivo response to endotoxin b...

摘要：Laminar shear stress (LS) promotes endothelial cell (EC) quiescence, whereas oscillatory shear stress (OS) promotes EC turnover and dysfunction, which could lead to pathological angiogenesis。Lamin...

摘要：Cytokine Growth Factor Rev。 Cytokine Growth Factor Rev。 Cytokine Growth Factor Rev。

摘要：Materials and MethodsZebrafish Care and BreedingAll studies conformed to Home Office requirements for use of animals in scientific experiments。 Fli1:eGFP transgenic zebrafish (expressing endotheli...

摘要：derived vascular endothelial growth factor receptor-2 (VEGF- R 2)&ndash。positive cells can differentiate into both vascular endothelial cells and mural cells。 This time, we investigated kinetics ...

摘要：Reactive hyperemia is the compensatory increase in blood flow that occurs after a period of tissue ischemia, and this response is blunted in patients with cardiovascular risk factors。 【...

摘要：VSMC biology depends in part on polyamines whose metabolism is closely regulated by ornithine decarboxylase antizyme 1 (OAZ1)。 Therefore, we sought for association between OAZ1 gene polymorphisms ...