摘要：1 Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine 2 The Wistar Institute, Philadelphia, PA 19104 Selection of recently formed B cells into the follicu...

摘要：Despite successes in many differential murine models, rational and efficient translation to the clinic has been difficult。 The major barriers delaying the translation of basic research that were a...

摘要：1 Department of Microbiology and Immunology, International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo 108-8639, Japan 2 Department ...

摘要：however, only a small proportion induce measurable CD8+ T cell responses。 To investigate the factors that control peptide immunogenicity, we have examined the cytotoxic T lymphocyte (CTL) response...

摘要：1 Department of Cell Signaling, Graduate School 2 Department of Medicine and Rheumatology, Graduate School 3 Department of Cellular Physiological Chemistry, Graduate School 4 Center of Excellence P...

摘要：G5 Dynamiques des Réponses Immunes, INSERM 668, Département d‘Immunologie, Institut Pasteur, 75015 Paris, France The cellular mode of T cell priming in vivo remains to be characterized fully。 W...

摘要：1 Department of Microbiology and Immunology, University of Melbourne, Melbourne, Victoria 3010, Australia 2 Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria 3002, Austr...

摘要：1 Division of Molecular Life Sciences and College of Pharmacy, Ewha Womans University, Seoul, Korea 121-742 2 Department of Immunology and Infectious Diseases, Harvard School of Public Health 3 Dep...

摘要：1 Department of Microbiology and Immunology, Weill Cornell Medical College, New York, NY 10021 2 Department of Neurology and Neuroscience, Weill Cornell Medical College, New York, NY 10021 3 Depart...

摘要：19:837–847) established the unique capacity of DNA and DNA-associated autoantigens to activate autoreactive B cells via sequential engagement of the B cell antigen receptor (BCR) and Toll-like rec...

摘要：1 Laboratory of Virology and Infectious Disease, Center for the Study of Hepatitis C, The Rockefeller University, New York, NY 10021 2 Cornell/Rockefeller/Sloan-Kettering Tri-Institutional MD-PhD P...

摘要：1 Department of Molecular and Integrative Neurosciences, The Scripps Research Institute, La Jolla, CA 92037 2 Department of Infectology, The Scripps Research Institute, La Jolla, CA 92037 3 Laborat...

摘要：Vincent‘s Institute of Medical Research, Fitzroy, Victoria 3065, Australia 4 The Protein Crystallography Unit, Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victori...

摘要：Epidemiological studies, however, indicate that Th2 cell–stimulating helminth parasites may also counteract allergies, possibly by generating regulatory T cells which suppress both Th1 and Th2 arm...

摘要：, Houston, TX 77025 We recently showed that dendritic cells (DCs) activated by thymic stromal lymphopoietin (TSLP) prime naive CD4+ T cells to differentiate into T helper type 2 (Th2) cells that pr...