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| 【英文篇名】 | Generation of reference fingerprint using principal component analysis |
| 【作者】 | 聂磊; 胡震; 罗国安; 王义明; |
| 【英文作者】 | NEI Lei~1; HU Zhen~（1; 2）; LUO Guo-an~（1*）; WANG Yi-ming~1（1. Pharmacy Institute of Tsinghua University; Beijing; China; 2. School of Life Science and Technology of Xi\'an Jiaotong University; Xi\'an; China）; |
| 【单位】 | 清华大学药物研究所; 北京100084西安交通大学生命科学与技术学院; 陕西西安; |
| 【刊名】 | 中成药 , 编辑部邮箱 2005年 06期 中文核心期刊要目总览 ASPT来源刊 CJFD收录刊 |
| 【英文刊名】 | Chinese Traditional Patent Medicine |
| 【中文关键词】 | 对照指纹图谱; 主成分分析; 色谱指纹图谱; |
| 【英文关键词】 | reference fingerprint; principal component analysis; chromatographic fingerprint; |
| 【中文摘要】 | 目的:本文提出一种对照指纹图谱生成的新方法:主成分分析法。方法:以痛必定粉针和多波长栀子色谱指纹图谱为例,采用主成分分析法生成对照指纹图谱。并与均值法和中位数法进行了比较。结果:主成分分析法基于最小二乘原则,生成的对照图谱是原始样本图谱的线性组合,对原始指纹图谱的数据信息具有较好的概括能力和优化性能,且与均值法和中位数法得到的结果非常相近。在有异常样本存在时,主成分分析法可以方便地观察和发现可能的异常样本,及时采取措施消除异常样本的影响。结论:主成分分析法可以作为一种对照指纹图谱生成的有效方法。 |
| 【英文摘要】 | AIM: A novel approach to generate reference fingerprint, named principal component analysis method(PCA), was proposed in this paper. METHODS: Chromatographic finerprint of Tongbiding Injection and multi-wavelength chromatographic fingerprint of Fructus Gardenia were served as examples. Their corresponding reference fingerprints were yielded via PCA, and by comparison with average method and median method were also performed. RESULTS: Reference fingerprint, yielded by PCA based on least-squares principle, wa... |
| 【DOI】 | CNKI:ISSN:1001-1528.0.2005-06-000 |