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| [中文名称] | 堆心菊苦素 |
| [英文名称] | Heleniamarin |
| [别 名] | |
| [化学名称] | 2H-1,4-Dioxabicyclopent [cd,f]azulene-3,9-dione-3,9-dione, 2a,4a,5,6,8,9a,9b,9c-octahydro-2-hydroxy-2,2a,6,9a-tetramethyl-, [2S-(2α,2aβ,4aα,6β,9aα,9bβ,9cβ)]- |
| [分 子 式] | C17H22O5 |
| [分 子 量] | 306.14 |
| [物理性质] | 棱柱状结晶(乙醚), 熔点151～153°, (α)25D+58.5°(C=0.25, 氧仿) 。LRλKBrmax cm-1: 3450(br.), 1755(sh), 1750; UVλMeOHmax nm(ε): 278(66),226(335); MSm/e(％): 306, 283(3), 264(30), 246(3), 235(100); NMR(CDCI3)δ: 1.22(s,3H), 1.23(d, J=7), 1.28(s,3H), 150(s,3H), 2.82(t,J=2,1H), 2.97(t,J=2,1H), 3.60(s,1h,与D2O可交换), 4.07(d,J=6.6,1H), 5.03(br,t,J=1,1H), 5.78(br.s,1h) 。 |
| [成分分类] | |
| [药理作用] | 对人体鼻咽癌(KB)细胞有细胞毒活性 |
| [毒 性] | |
| [不良反应] | |
| [用 途] | |
| [成分来源] | 菊科植物苦味堆心菊 Helenium amarum (Rafin.)H. Rock. |