[摘要] 分析处方药市场动态和研发趋势将对我国“十一五”生物医药发展战略的确立提供有意义的参考。全球人用处方药市场近5年发展迅速,其销售额连续突破了4000、5000和6000亿美元等“多零”关节点,已经成为21世纪经济快车的重要引擎之一。世界“50强”和“10强”制药企业销售额合计分别占总额的70-78%和42-58%;2005年,“50强”和“10强”的R&D 投入分别是750亿美元和450亿美元左右。年销售额超过10亿美元的“重磅炸弹”总数为94个,降血脂药物销售稳定地排在首位,抗
肿瘤药物近两年增长最快;生物制品连续2年增长率大于17%。新批上市药物呈现了下降趋势。
[关键词] 处方药;全球销售;新药研发; 发展战略
Analysis of trends of human prescription drug global sale and research and development
of new drug
WU Wei-xing1, YANG Ning1, WANG Xiao-ning2
1.Institute of Transfusion Medicine, Academy of Military Medical Sciences, Beijing
100850, China
2.School of Bioscience and Bioengineering, South China University of Technology
Analysing and understanding of marketing dynamics of human prescription
drug and trends of research and development of new drug provide comprehensive information
to strategy making of biomedicine for next five years in China. Market of human prescription
drug has been developing very fast during last five years, the total sale has break through
multi-zero points of 400, 500 and 600 billion US dollars, and the market has become one
of important engines of 21st century economic train. The world’s top 50 and top 10
pharmaceutical companies have gained 70-78% and 42-58% of the market share respectively.
The top 50 and top 10 invested 75 and 45 billion US dollars respectively in 2005.
There are 94 blockbusters, cholesterol and triglyceride reducers has ranked no. 1,
anti-cancer drugs has increased at the fastest rate in last two years; biologics
grew by more than 17% for the second year in a row. The number of launched new drug
decreased.
[key words] prescription drug; global sale; research and development of new drug;
strategy making
处方药是生物医药的主流药物,其研发和销售的动态不但影响整个医药领域的发展,而且由于其已成为全球经济增长的支柱性产业之一,也直接影响全球经济增长。由于技术的进步,特别是各种组学和通量筛选、评价新药技术的迅猛发展,以及西方发达国家和医药寡头为顺应市场需求的不确定变化而做出的各种政策及战略调整,使得全球处方药的研发销售仍保持着强劲发展的势头,形成更为巨大的市场, 2001-2005年之间,连续突破了4000亿美元、5000亿美元和6000亿美元等“多零”关节点。我国生物医药在过去几年里也有了突破性的进展,增长速度也超过了平均国民经济的增长速度,并期待在“十一五”期间有跨越式的发展,逐步成为我国经济增长的支柱产业。研究和分析全球处方药的研发销售动态变化和趋势,探讨影响和限制其发展的内外因素无疑地能为确立我国“十一五”生物医药发展战略提供有意义的参考。本文基于生物医药权威杂志对全球医药寡头的系列年报对2001-2005年全球人用处方药物的销售特点及趋势进行了归纳总结,并在此基础上对其形成的内外因素进行了分析,结合国内医药研发销售的现状,提出一些建议,以期对业内和政府在确定医药研发战略时提供参考。
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吴卫星1 杨宁1 王小宁2
1、军事医学科学院输血医学研究所 北京100850
2、华南理工大学生物科学与工程学院 广州510640
作者: