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| 【英文篇名】 | HPLC fingerprint analysis and chemical pattern recognition of Fructus aurantii |
| 【作者】 | 赵宇; 谢培山; 梁逸曾; 杨辉; 易伦朝; |
| 【英文作者】 | ZHAO Yu; XIE Pei-shan; LIANG Yi-zeng; YANG Hui; YI Lun-zhao （ Research Center Modernization of Chinese Medicines; Institute of Chemometircs and Intelligent Analysis Instruments; College of Chemisty and Chemical Engineering; Central South University; Changsha; China; Keman Research Institute of Traditional Chinese Medicine; Zhuhai; College of Chemists and Chemical Engineering; China）; |
| 【单位】 | 中南大学化学化工学院中药现代化研究所; 广东珠海科曼中药研究所; 中南大学化学化工学院; |
| 【刊名】 | 中国药学杂志 , 编辑部邮箱 2005年 11期 中文核心期刊要目总览 ASPT来源刊 中国期刊方阵 CJFD收录刊 |
| 【英文刊名】 | Chinese Pharmaceutical Journal |
| 【中文关键词】 | 枳壳; 指纹图谱; 高效液相色谱法; 化学模式识别; 质量控制; |
| 【英文关键词】 | Fructus aurantil; fingerprint; HPLC; chemical pattern recognition method; quality assessment; |
| 【中文摘要】 | 目的初步建立中药枳壳质量控制的模式识别方法方法。采用高效液相色谱对收集到的枳壳样品进行指纹图谱分析。运用相关系数计算和基于主成分分析的投影显示法对实验数据进行模式识别研究。结果枳壳指纹图谱分析与化学模式识别结果显示,大部分枳壳药材与江西地道药材成分相近,聚为一类;少数几个样品成分与江西类药材有差异。结论从药材的判别结果来看,多数样品与道地药材成分相近,从传统用药的角度出发,可近似认为它们质量优良,从而初步为枳壳药材质量优劣建立简单、快速的判别方式。 |
| 【英文摘要】 | OBJECTIVE To establish the chemical pattern recognition method for the quality control of Fructus aurantii. METHODS The flavonoids in the samples were extracted with methanol and determined by HPLC with non-linear gradient elution. The mobile phase consisted of methanol,aoetonitrile and 0.05% phosphoric acid. The fingerprints of 18 samples were obtained and handled by the chemical pattern recognition method. RESULTS The result of chemical pattern recognition method indicate that most of the samples collecte... |
| 【DOI】 | CNKI:ISSN:1001-2494.0.2005-11-004 |